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Waklert (Armodafinil)
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Armodafinil

In patients with excessive sleepiness associated with chronic SWD of moderate or greater severity, Waklert significantly improved wakefulness during scheduled night work, raising mean nighttime sleep latency above the level considered to indicate severe sleepiness during the daytime.

Other names for this medication:
Armodafinil, Waklert, Armod, Nuvigil,

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Waklert is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). Waklert is also used along with breathing devices or other treatments to prevent excessive sleepiness caused by obstructive sleep apnea/hypopnea syndrome (OSAHS; a sleep disorder in which the patient briefly stops breathing or breathes shallowly many times during sleep and therefore does not get enough restful sleep). Waklert is in a class of medications called wakefulness-promoting agents. It works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness.

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Family Caregivers of Patients With a High-Grade Glioma: A Qualitative Study of Their Lived Experience and Needs Related to Professional Care. Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes. Racemates and their individual enantiomers can have very different pharmacological properties that are relevant in clinical psychopharmacology.

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Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk. Intraoperative hydroxyethyl starch 70/0.5 administration may increase postoperative bleeding: a retrospective cohort study. Measurements of blood pressure, heart rate and renal, mesenteric and hindquarters haemodynamics were made in conscious, chronically-instrumented rats. These findings suggest an inverse-relationship between inflammation and purine deaminases in both blood and tissues.

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By methanol extraction and high-pressure liquid chromatography a nonprotein chromophore has been obtained from the antitumor protein antibiotic auromomycin (AUR) which possesses the cytotoxic and the in vivo and in vitro deoxyribonucleic acid (DNA) strand scission activities of the parent material. Tick-borne relapsing fever in the Pacific Northwest: an underdiagnosed illness? Our results show that the integration of the response to different stimuli requires complex interconnections between signaling pathways. These results indicated that both the proteinic and polysaccharidic antigens carried species-specific epitopes. Dividing the residents into three groups, we compared the effect of concurrent chart review and discussion in one group with the effect of a moderate financial incentive for limited ordering of tests in a second group.

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Association of platelet count with residual thrombus in the myocardial infarct-related coronary artery among patients treated with fibrinolytic therapy for ST-segment elevation acute myocardial infarction. Large-scale synthesis of micrometer-scale single-crystalline Au plates of nanometer thickness by a wet-chemical route.

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Other dietary components, especially omega-3 polyunsaturated fatty acids and lignans in foods like flax seed, also exert favorable effects on estrogen metabolism. We used logistic regression analyses to determine the association between gentamicin use and the number of days alive and free of renal failure, shock, and death, all on day 14. The objective of this study was to investigate prognostic factors, recurrence patterns and survival endpoints in this group of patients. Polypyrrole (Ppy) was selected as a matrix for preparation of MIP.

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Computational predictions have greatly accelerated the discovery of microRNAs. All these functions improved after pharmacological treatment, as well as quality of life, depressive and anxiety symptoms, and daytime sleepiness. The coexpression of p125 with p48 resulted in an increased accumulation of p125 in the nucleus, indicating that p48 plays a critical role in the nuclear localization of p125. External locus of control and quality of life among Malaysian breast cancer patients: The mediating role of coping strategies. Osteoporosis in celiac disease and in endocrine and reproductive disorders.

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To discuss the impact of different markers on the estimation of MSM using the capture-recapture method. Within a few hours this technique can efficiently generate anatomical images that are not obtainable with conventional methods, thus demonstrating a new and exciting approach to invertebrate research. Our findings could explain tPA generation in wound epidermis is at least partially controlled by changes in local IL-1alpha activity, and will contribute to our understanding the physiological effects of IL-1alpha and TGF-beta1 as well as their interaction of with the PA system during skin wound healing. Investigation of the translational and orientational dynamics via single molecule fluorescence techniques gives structural as well as dynamical information about the host material.

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Low-grade steatosis and major changes in portal flow as new prognostic factors in steroid-treated alcoholic hepatitis. Exome sequencing analysis of over 2,000 children with complex malformations of cortical development identified five independent (four homozygous and one compound heterozygous) deleterious mutations in KATNB1, encoding the regulatory subunit of the microtubule-severing enzyme Katanin.

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Apoptosis was observed in the photoreceptor layer of Cln3 knockout. A Label-Free Microelectrode Array Based on One-Step Synthesis of Chitosan-Multi-Walled Carbon Nanotube-Thionine for Ultrasensitive Detection of Carcinoembryonic Antigen.

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Crystal networks in silk fibrous materials: from hierarchical structure to ultra performance. Update on inhaled corticosteroids: safety, compliance, and new delivery systems.

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These subgroups could be presumed to benefit from different treatment regimens, which should be further investigated. In Shwachman-Diamond syndrome (SDS), a defective SDBS protein prevents eIF6 eviction, inhibiting its recycle to the nucleus and subsequent formation of the active 80S ribosome. The proteome of an organism is the protein complement of its genome. We have previously shown that normal children have an upper airway that is resistant to collapse during sleep.

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