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Tolep (Oxcarbazepine)

Tolep is used alone or with other medications to treat seizure disorders (epilepsy). It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name eslicarbazepine.

Other names for this medication:
Oxcarbazepine, Trileptal, Actinum, Apydan, Auram, Aurene, Deprectal, Leptal, Oxcarbazepin, Oxcarbazepina, Oxetol, Oxicodal, Tolep,

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Finlipol, Tabalon, Fluconapen, Amotaks, Flotral, Hipres, Bicalutamide, Fexidine, Almazine, Dumozol, Panwarfin, Lamictal, Olprezide, Equetro, Lavisa, Oroken, Gabrion, Topictal, Ostan, Afenac, Lansoprazol, Bystolic, Parkizol, Eurythmic, Progen, Finahair, Restream, Ulcotenal, Dolodol, Progut, Surpass, Azeptin, Selam, Disys,

Tolep comes as a tablet, an extended-release tablet, and a suspension (liquid) to take by mouth. The tablet and suspension are usually taken every 12 hours (twice a day) with or without food. The extended-release tablet is usually taken once a day on an empty stomach, 1 hour before or 2 hours after a meal. Take Tolep at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Tolep exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well right before each use to mix the medication evenly. Use the oral dosing syringe that came with the medication to withdraw the right amount of suspension from the bottle. You can swallow the suspension straight from the syringe or you can mix it with a small glass of water and swallow the mixture. Wash the syringe with warm water and allow it to dry thoroughly after use.

Swallow the extended-release tablets whole with water or another liquid; do not split, chew, or crush them.

Your doctor will probably start you on a low dose of Tolep and gradually increase your dose, not more often than once every 3 days. If you were taking another medication to treat your seizures and are switching to Tolep, your doctor may gradually decrease your dose of the other medication while increasing your dose of Tolep. Follow these directions carefully and ask your doctor if you are not sure how much medication you should take.

Tolep may help control your seizures but will not cure your condition. Continue to take Tolep even if you feel well. Do not stop taking Tolep without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking Tolep, your seizures may get worse. Your doctor will probably decrease your dose gradually.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with Tolep and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( or the manufacturer's website to obtain the Medication Guide.

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