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Plagerine (Clopidogrel)
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Clopidogrel

Plagerine bisulfate (Plagerine) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Plagerine prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class of drugs called P2Y12 inhibitors. Other drugs in this class include ticagrelor (Brilinta) and prasugrel (Effient). Plagerine is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, Plagerine bisulfate does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack, and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking.) Plagerine bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Plagerine bisulfate was approved by the FDA in 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Plagerine comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take Plagerine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Plagerine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Plagerine will help prevent serious problems with your heart and blood vessels only as long as you take the medication. Continue to take Plagerine even if you feel well. Do not stop taking Plagerine without talking to your doctor. If you stop taking Plagerine, there is a higher risk that you may have a heart attack or stroke. If you have a stent, there is also a higher risk that you could develop a blood clot in the stent if you stop taking Plagerine too soon.

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The purpose of this study was to determine the extent to which nursing assessment was performed by the nurses and to identify the nursing diagnostic domains being frequently utilized in the study setting. A 20-kDa allergen was purified from the abdominal muscle of black tiger shrimp by salting-out, anion-exchange HPLC and reverse-phase HPLC.

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Cel9D, an atypical 1,4-beta-D-glucan glucohydrolase from Fibrobacter succinogenes: characteristics, catalytic residues, and synergistic interactions with other cellulases. Dilution kinetic studies of yeast populations: in vivo aggregation of galactose utilizing enzymes and positive regulator molecules. Nucleolar organizer regions in neoplastic and non-neoplastic epithelium of the cervix. Affinity mass spectrometry is a negative myoclonus gabapentin dosage proteomics approach for selectively isolating target proteins from complex biological fluids for mass spectrometric analysis. It is not clear whether the presence of aPL is a risk factor for thromboembolism or do they directly take a part in thrombogenesis.

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