Miol is used to treat certain conditions where there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. Sometimes Miol is used in combination with antibiotics (eg, amoxicillin, clarithromycin) to treat ulcers associated with the infection caused by the H. pylori bacteria.

Miol is also used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid.

Miol is also used to treat dyspepsia, a condition that causes sour stomach, belching, heart burn, or indigestion.

In addition, Miol is used to prevent upper gastrointestinal tract bleeding in seriously ill patients.

Miol is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.

This medicine is available both over-the-counter (OTC) and with your doctor's prescription.

This product is available in the following dosage forms:

• Powder for Suspension
• Tablet Disintegrating, Delayed Release
• Capsule, Delayed Release
• Tablet, Delayed Release
• Packet

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The specific retention volume increased with increasing probe chain length, decreased with increasing column temperature, and increased with increasing maleated polypropylene concentration. The aim of this study was to examine whether NGF can play a role in the pathology of oral lichen (OL).

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Following current considerations of insulin signals regulating GLUT4, this review will focus on in vitro and in vivo evidence that supports an essential role for phosphoinositides and actin filaments in the control of glucose transport. The Rocky Mountain Center for Occupational and Environmental Health. This survey seeks to extend our knowledge of the relationship of sexual attitudes and preferences to sexual functioning of a large group of older, community-dwelling men. Although IMTs in some organs are not uncommon, they are not usually included in the differential diagnosis of masses.

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This paper primarily reviews experimental data from our laboratory based on direct conductance measurements during whole-cell patch clamp recordings in two experimental preparations: (1) in vitro, during electrical stimulation in the visual cortex of the rat and (2) in vivo, during visual stimulation, in the primary visual cortex of the anaesthetized cat. Our data show that pancreatic duct cells express prominin-1 and surprisingly reveal that its particular AC133 epitope is not an exclusive stem and progenitor cell marker.

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These data suggest that the induction of GST-P by HNE may represent an important cellular defense mechanism against oxidative injury. Because bottlenecks have occurred in the history of numerous species, we undertook a simulation approach to investigate their impact on the patterns of aggregation of polymorphic sites and linkage disequilibrium (LD). We therefore characterized 20 different integration sites of the Sacchromyces cerevisiae genome by inserting lacZ as a reporter gene under the control of two different promoters and determining expression levels through enzyme activity measurement.

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The corticosteroid-induced skin blanching from four different betamethasone 17-valerate cream formulations was compared in a typical human skin blanching trial. The use of synthetic dyes for identification of the amniotic sacs in multiple pregnancies. These findings suggest that genetic factors may give rise to dispositional tendencies to experience both pleasant events and depression. Two patients who underwent successful shunting for hydrocephalus subsequently developed thickening and diffuse signal changes in the corpus callosum, which were revealed by magnetic resonance imaging. Constipation and encopresis frequently cause problems with respect to emotional wellbeing, and social and family life.

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Results were compared with genotypes, gender of the patients, and biochemical markers of active hepatitis. These findings suggest an indirect role for mGluR1 in synaptic plasticity via a regulation of GABA inhibition. This effect was prevented by 10(-6) mol losartan or by 10(-6) mol captopril. In conclusion, kirromycin can substitute for GTP, aminoacyl-tRNA, or ribosomes in various reactions involving EF-Tu, apparently by affecting the allosteric controls between the sites on the EF-Tu molecule interacting with these components. A 20-month-old girl with developmental delay, dysmorphic features, horizontal supranuclear gaze palsy, retrocollis, and episodes of laryngospasm was diagnosed with variant neuronopathic Gaucher disease.

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Eight amino acid residues at EpoB C terminus, in which six are positively charged, were found to be a key component of the C-terminal linker effect. As a major product of membrane lipid peroxidation, 4-hydroxynonenal (HNE) appears after various kinds of oxidative stress, and is known to induce cell growth inhibition. Synthetic molecules that modulate transcription and differentiation: hints for future drug discovery. The 2nd case was a 47-year-old woman who had received cadaveric renal transplantation.

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This is a report of a novel inherited form of RD that affects American pit bull terriers. A one-step synthesis of magnetic nickel nanowires (NiNWs) with tunable characteristics is reported.

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In chronic musculoskeletal pain, avoidance behavior is a prominent behavioral characteristic that can manifest itself in various ways. Topiramate use in obese patients with binge eating disorder: an open study. The regions within the N-terminus critical for human glucagon like peptide-1 receptor (hGLP-1R) cell surface expression. Simulation results are shown to be compatible with experimental data. The cases illustrate the challenges and issues on the critical decisions of diagnosis, resuscitation, and whether the flight had to be returned or diverted.

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Sulfamethazine was fed to weanling pigs at the rate of 100 g/ton of ration for 98 days to investigate the depletion rate of the drug from the plasma and edible tissues of swine. Ulinastatin or urinary trypsin inhibitor (UTI) has been shown to ameliorate the inflammatory response induced by experimental severe acute pancreatitis (SAP) and hence reduce the mortality, however the mechanism of its action remains incompletely understood. Our results showed that the synthesized nanoparticles had no toxic effect on any of the cell lines used. Patients with synchronous colorectal cancers, inflammatory bowel disease, previous colorectal resection, loss to follow-up, and incomplete resection were excluded. The English language literature on the epidemiology of dual diagnosis is reviewed.

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Kinetic study of blood cortisol during coma: changes in the circadian rhythm A Southern blot analysis and PCR with degenerated primers were carried out to detect the presence of fks1-like genes in these Basidiomycetes. The intrinsic activities of five GCAP1 promoter-luciferase constructs were measured in transiently transfected primary chicken embryonic retinal cultures.

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To develop an instrument for sacroiliac joint fixation with less injury and less complications. The redox properties and the nature of the electro-active species of the complexes have been characterized. Mechanism of hypertensive nephropathy in the Dahl/Rapp rat: a primary disorder of vascular smooth muscle. Frequent, sensitive and accurate sampling of Anopheles mosquitoes is a prerequisite for effective management of malaria vector control programmes.

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Changes in peripheral blood are reflected in alterations in cell kinetics, transferrin receptor expression and markedly increased apoptosis and cell death in the bone marrow indicating that TNF-alpha may contribute to myelodysplasia in ACD. RAW 264.7 macrophages also showed a robust chemotactic response towards CT26-derived chemokines. It found that around three-quarters of those not working have been able to avoid low-income status. This paper presents a comparison of the two techniques and the morphine concentrations determined in blood. In the meantime, an analysis was also made on key issues, such as adverse reactions of TCMIs, modern clinical application, special drug delivery route and diversity of components and ingredients.

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Incubation of three stabilized BLA variants with several proteases showed that all tested isolates have significantly increased resistance to proteolysis. An in vitro assay system was optimized to study binding of capacitated human sperm to ZP3 coated beads. Maximizing the health of women with epilepsy: science and ethics in new drug development. The age-related factors might play important roles in the development of IgAN. TSP-1 is overexpressed in MPM tumors but its expression is of little value as a prognostic indicator in MPM.

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It is unknown how precisely the donor meniscus needs to fit the size of the original meniscus to allow healing and regeneration. All three antibody pools were reactive towards their respective antigens upon Western blot analysis.

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Envelope of mouse mammary tumor virus studied by freeze-etching and freeze-fracture techniques. Nutrition in pregnancy complicated by concomitant liver and biliary tract diseases These results highlight that both the Tat substrate and ubiquitin modification have plastic site usage, and this plasticity is likely another way in which the virus exploits the host molecular machinery to expand its limited genetic repertoire.

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SMCs from elderly persons have limited proliferative capacity and a reduction in collagen production, which impair the mechanical strength of engineered vessels. Thus, our results demonstrate the inhibitory effect of activated carbon fiber adsorbent Aqualen on intestinal carcinogenesis in rats. From this work, the authors concluded that quinine has essentially intracellular targets involved in drug distribution (cytoplasm to nucleus) from sequestration compartments.

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Using genetically deficient mice, we explored the role of uPAR in platelet kinetics and TNF-induced platelet consumption. Increased biopotential power in drug dependence persons was observed at left temporal hemisphere in high-frequency bands in baseline interval and during olfactory stimulation. Since data from animal breast tumors and preliminary evidence from human breast tumors indicates an excellent correlation between the presence of abundant tumor EBP and endocrine-induced breast cancer regressions, precise quantitation of EBP in all human primary tumors may prove to be an excellent prognosticator of endocrine therapy in metastatic breast cancer. The recommended long-term medical treatment with conventional or atypical antipsychotics of patients after discharge and the one year rehospitalization rate depending on the medical treatment at time of discharge were examined.

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This is costly and inconvenient for the patient, and there is a need for a simple pregastroscopic screening method to reduce the endoscopy workload. An institution-based survey was conducted in all orphanages in Turkey and included 6,220 adolescents. Thus, in addition to the well-characterized dependence of taste bud maintenance on the chorda tympani nerve, the present study shows an additional role of the chorda tympani nerve in papilla maintenance during early postnatal development. In this review we discuss available data on a set of modification sites in the most studied bacteria, Escherichia coli.

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All lactobacilli under study produced a pronounced bactericidal effect on Pseudomonas, had different influence on the viability of Escherichia and staphylococci and exhibited fungistatic and fungicidal action only when inoculated at high concentrations. Our objective was to evaluate the diagnostic performance of endobronchial ultrasound (EBUS) to detect cancer in patients with radiographically abnormal mediastinal lymph nodes.

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We sought to assess the accuracy of adolescent self-report of sexually transmitted diseases (STDs) and pregnancies. Gastro-oesophageal reflux is common in patients with sleep disorders, is associated with increased arousal, decreased durations spent in the deeper stages of sleep and poorer sleep-related quality of life. Sequences of the ubiquitin-conjugating enzyme (UBC or E2) family were used as a test set to investigate issues associated with the high-throughput comparative modelling of protein structures. Solubilization of the vesicles increased the affinity for calcium, suggesting that in an intact bilayer the dimer interface is not properly formed. The number of previous surgeries and axial length, rather than the nature of the previous surgical procedures, were significant prognostic factors for anatomic success after silicone oil removal.

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The influences of neonatal hyperbilirubinemia and respiratory complications were examined in 5- to 11-month-old infants in two studies. Likewise, myotube assembly of C2C12 cells was profoundly influenced by aligned topographic features resulting in enhanced myotube organization and length.

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Proximal femoral reconstruction for failed internal fixation of a bisphosphonate-related femur fracture. Status report, Department of Pharmacology, University of Nebraska Medical Center. TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.

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Effects of multisystemic therapy on caregivers of serious juvenile offenders: A 20-year follow-up to a randomized clinical trial. A high-level feedback control approach for rapid imaging in atomic force microscopy is presented.

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The precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Late diagnosis of HIV infection: major consequences and missed opportunities.

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The combination of QX-314 and bupivacaine facilitated prolonged sciatic nerve block in rats with a satisfactory safety profile, maximizing the duration of nerve block without clinically important systemic and local tissue toxicity. Acute toxicity of metals and reference toxicants to a freshwater ostracod, Cypris subglobosa Sowerby, 1840 and correlation to EC(50) values of other test models. A conjugate of ristomycin A ristosaminylaglycon-polymyxin B: the spectrum of its antimicrobial action and its membranolytic activity Reduction of exposure to laboratory animal allergens in the workplace.

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First, a decentralized tracking approach is adopted so that the tracking can be implemented energy-efficiently and steadily. However, different sizes and/or preparations of mercaptocarboxylic acid solubilized QDs show very different properties when incubated with cells.

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The applicability of an etched and silver or gold coated SERS fiber probe in combination with a commercially available laboratory micro-Raman setup or a home built mobile micro-Raman setup to perform on-site field measurements was evaluated and successfully tested on different biological samples. Anthracycline cardiotoxicity remains a serious problem in paediatric and adult cancer survivors, and the advancement of cardio-oncology is a necessary step for an effective care of the patients that experience adverse cardiovascular effects. The greater numbers of neutrophils in gp91(phox)(-/-) mice were not associated with increased lung injury.

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Regardless of relationship status, participants also reported improvement in general relationship and communication skill. This brief scale is a promising means of assessing potentially modifiable aspects of the intimate partner relationship in the postnatal period. The gene encoding a 10-kDa acyl-CoA-binding protein (ACBP) from Brassica napus was over-expressed in developing seeds of Arabidopsis thaliana.

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These mutants were subsequently inoculated onto the model plant Nicotiana benthamiana, as well as tomato, to evaluate their accumulation levels, symptom severities, and cross-protection potentials. Children with early mathematical difficulties showed poor performance in both verbal and visuospatial WM tasks as well as on language tests and a fluid intelligence test indicating a thoroughly lower cognitive base. The potential future therapeutic modalities include alternative medicine, pharmacologic treatment of the epileptogenic focus, genetic treatment and vaccination. Spectrum of conduction abnormalities associated with maternal anti-Ro antibodies.

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Pregnant with possibilities: drawing on hermeneutic thought to reframe home-visiting programs for young mothers. It has been suggested that interleukin-6 (IL-6) is a prognostic indicator for survival in patients with gastric carcinoma, but this has not been proved using survival analysis. Juvenile angiofibroma: a more rational therapeutic approach based upon clinical and experimental evidence. The cusp tensile properties of supercritical carbon dioxide treated valves were higher compared to valves treated with other techniques. Thus 35 studies covering more than 100 years have been included.

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Criminal and civil suit data for caregivers were obtained during a 20.7-year follow-up when caregivers were on average 61.5 years old. Distribution of antimicrobial resistance determinants, virulence-associated factors and clustered regularly interspaced palindromic repeats loci in isolates of Enterococcus faecalis from various settings and genetic lineages. Concurrently, the dog had chronic eosinophilic hepatitis with impaired liver function and mesenteric eosinophilic lymphadenitis. Bradycardia Associated with Prednisolone in Children with Severe Kawasaki Disease. The most commonly used reverse genetics system is the infectious clone technology.

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Although peripheral blood lymphocyte responses were very low or absent, abomasal lymph node lymphocytes of exposed animals showed a strong response to the L3 antigen extract. The main reason proposed to explain this lower sensitivity is that the highly reduced flow distal to occluded or highly stenotic segments increases the difficulty of detecting significant Doppler velocity changes in the distal or secondary stenoses.

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Clinical and histological similarities between hidradenitis suppurativa and acne have been pointed out. The use of a mechanical suture of the ribs as a component in the complex treatment of patients with a thoracic trauma is an efficient method in the struggle against posttraumatic respiratory insufficiency and shock. Far-infrared laser system for detection of defects in polyethylene-insulated power cables. It is it the obligation of fellow humans and society in general to preserve and dignify human life and to care for the total needs of individual citizens to enable them to be healthy and productive members of society. Conjugate addition/Ireland-Claisen rearrangements of allyl fumarates: simple access to terminally differentiated succinates.

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A perforating keratoplasty was performed, and two small pigmented iris nodules were now noted. A clinician-focused pharmacogenomics information resource can answer pharmacogenomics-related medication questions faster, more correctly, and more easily than widely used alternatives, as perceived by pharmacists. We report a case of a giant serpentine aneurysm of the right middle cerebral artery (MCA) that was treated by total excision of the aneurysm with cerebral blood flow control management. In both controls and DMSO-exposed human oocytes, chromosomes were arranged on the metaphase equatorial plate.

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Despite this controversy, testosterone supplementation in the United States has increased substantially over the past several years. By analysis of null mutants of RPS4 and RRS1 in Col-0 we show that these genes, individually, do not contribute strongly to C.

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This article reviews selected publications related to nonsteroid anti-inflammatory drug (NSAID)-induced gastroduodenal toxicity in recent years. There are still only a limited number of studies regarding the neuroprotective effects of hyperthermic preconditioning on regional brain ischemia or regarding the role of adenosine A1 receptors in such pretreatment. Tractography provides a reliable method for early assessment of perinatal brain injury. Vascularized grafts and the timing of nerve grafting also are discussed. Umbilical blood flow response to embolization of the uterine circulation.