Locin is used to treat bacterial infections in many different parts of the body. It is also used to treat anthrax infection after inhalational exposure. Locin is also used to treat and prevent plague (including pneumonic and septicemic plague).

Locin belongs to the class of medicines known as quinolone antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Solution
• Tablet

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This research examines how successful recommended longterm medical treatment of schizophrenic patients is following their discharge from inpatient treatment by evaluating the yearly rehospitalization rates. We observed the evolution of increased virulence, growth rate, and public goods cheating (exploitation of extracellular iron scavenging siderophores produced by ancestral populations) in mutator but not wild-type, populations. The incidence of cutaneous malignant melanoma continues to increase every year, and this disease remains the leading cause of skin cancer death in industrialized countries. A prospective study on fact embolism showed that of ninety-five patients with a fractured shaft of the femur, seven (7 percent) demonstrated both pulmonary and cerebral disturbances, while there were profound disturbances in arterial PO2, hemoglobin level, pulse rate, and temperature in about 40 per cent of the patients.

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Supraspinal role of protein kinase C in oxaliplatin-induced neuropathy in rat. Neuropsychology of Aesthetic Judgment of Ambiguous and Non-Ambiguous Artworks. To observe the safety of slow-release transdermal fentanyl (TDF) used as anesthesia aided drug in endoscopic sinus surgery (ESS) peri-operation.

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Appropriate administration of this factor is essential for the success of its clinical application. This work demonstrates that ADAR is a component of two, distinct ribonucleoprotein complexes that contain different types of RNAs and exhibit diverse cellular localization patterns.

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More than 20 genes encoding sulfotransferases have been implicated in HS and CS/DS biosynthesis, and the functional repertoire of HS and CS/DS has been related to the expression of these isoenzymes. Tumours have evolved a variety of mechanisms to suppress host immune responses. Structure-activity relationship studies of the amide functionality in (p-O-sulfamoyl)-N-alkanoyl tyramines as estrone sulfatase inhibitors.

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and show the model can capture the impact of precision farm management on profitability. The xtalPIMS extension supports crystallogenesis and has recently been extended to support crystal fishing and crystal treatment. It is speculated that the quantitative and qualitative changes evoked by the NTP diet in BBdp rats may play a role in the alteration of gut permeability found under the same experimental conditions.

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Therapeutically Targeting the Inflammasome Product in a Chimeric Model of Endometriosis-Related Surgical Adhesions. The observation of this oxidatively induced chaperone/substrate complex suggests that an efficient chaperone-like protective action against oxidative insults may exist in vivo. There are few comparisons of Modic changes (MCs) in the lumbar and cervical spine. Detection of mouse mammary tumor virus in cat kidney cells infected with purified B particles from RIII milk.

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Hoof conformation, foot placement and movement asymmetry are routinely assessed as part of the lameness examination. The regulation and adjustment of PPARalpha activation underlying the balance of molecular cascades might resolve the progression of alcoholic liver diseases by reducing oxidative stress and inflammatory effects induced by nuclear factor-kappaB as well as the associated adiponectin pathway. Arthroscopic repair using Fast-fix is an idea method for meniscus injury, especially for the posterior horn tear of medial meniscus, which is simple and convenient with less complications, and satisfactory results. This article, the first in a set of two on the physiology of fever, focuses on the role of cytokines as the trigger for the physiologic cascade of fever.

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To improve the rate at which patients in detoxification programs are transferred to longer-term rehabilitation, more attention should be paid to medical conditions and to the direct consequences of drug use, such as withdrawal symptoms and craving during detoxification. The initially harmless-looking erythema of the skin rapidly transforms into a third-degree burn. The effect of Helicobacter pylori eradication on prokinetic treatment on the quality of life in functional dyspepsia

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A statistical model describing a fine structure of the intra-chromosome maps obtained by a genome-wide chromosome conformation capture method (Hi-C) is proposed. MRI analysis of the cerebellum in bipolar disorder: a pilot study.

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Effects of exercise training after open heart surgery on quality of life and exercise tolerance in patients with mitral regurgitation or aortic regurgitation. The PAPPy biosensor is free of interferences arising from ascorbic and uric acids, which allows its use for quantitative analysis in human blood serum.

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Fabrication of patterned polystyrene nanotube arrays in an anodic aluminum oxide template by photolithography and the multiwetting mechanism. Addition of 650mg/kg arsanilic acid enhanced the absolute abundances of tetC, sul2, ermB, and gyrA more than twofold in the digestion product.

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A complex of N-cadherin, plakoglobin, desmoplakin and vimentin was shown in motoneuronal cell cultures and peripheral nerves after injury in vivo. Thermochemistry of N-N containing ions: a threshold photoelectron photoion coincidence spectroscopy study of ionized methyl- and tetramethylhydrazine. Systemic sclerosis induces pronounced peripheral vascular dysfunction characterized by blunted peripheral vasoreactivity and endothelial dysfunction.

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A semi-realistic 3D model for tissue and blood vessels is used to analyze the transient heat transfer through the finger. A humanized monoclonal antibody targeting Staphylococcus aureus. We will briefly review some of the data to support such a concept. The findings suggest that a histologic grading system is an important adjunct to the clinical evaluation.

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Tea intake has been associated with lower risk of mortality and morbidity in some, but not all studies. Therefore, we have developed a complement-dependent model of TTP in rats by injecting monoclonal antibodies reactive with endothelial cells. This simple, brief bedside deep breathing test of heart rate variability in patients after myocardial infarction appears to be a good predictor for all-cause mortality and sudden death.

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Thirty-two healthy volunteers received a maximum of 1200 mg of OXC or 360 mg of PHT. This method was applied to eight fly ashes, adapted to the acidic or alkaline nature of the ash. This technique can be most useful in nonunions secondary to segmental bone defects or to large areas of nonviable bone. Automaticity of cognitive control: goal priming in response-inhibition paradigms. Differences among common oral antibiotics recommended by the American Thoracic Society are described.

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Communication between team members is critical in the delivery of quality care. It can be concluded that overcoming barriers related to patients and the system will lead to early-stage diagnosis, which in turn will result in higher survival rates of patients with breast cancer. The choice of clocks should be informed by the biology of the study group (e.g., life-form) or assessed with relative rate tests and post-hoc model comparisons.

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Different regulation of limb development by p63 transcript variants. Determining a field of specialty can be a difficult decision for medical students.

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Recurrent Mixed Cryoglobulinemia Despite Sustained Virologic Response to Treatment: A Case Report. Together, our theoretical model and empirical results suggest that, for yeast genes such as plasma-membrane transporters, elevated expression noise is advantageous, is subject to positive selection, and is a facilitator of adaptive gene expression evolution. Congestive cardiac failure is frequently encountered in diffuse hepatic hemangiomas due to high-volume shunting and rarely in hemangiomas confined to the skin. Female Sprague-Dawley rats were treated with MC (100 mumol/kg), ip, once daily for 4 days, and expression of CYP1B1 and several phase II (e.g., GST-alpha, NQO1) genes and their corresponding proteins were determined in lung and liver.

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We have designed a new polycentric knee adopting a hydraulic unit and an intelligent mechanism. Partial calcanectomy and Ilizarov external fixation may reduce amputation need in severe diabetic calcaneal ulcers. Thus, the total number of alleles may increase to five in another few million years. Either oxytocin (10 U) or ergometrine (0.25 mg) was given intravenously to patients having suction curettage for termination of pregnancy.

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Nox4, in contrast, potentially elicits positive effects because it promotes differentiation and reduces proliferation of cells. Synthesis of 6-formamidinopenicillanic acid derivatives of cyclic secondary amines The purpose of this study was to investigate whether excimer laser surgery affected corneal endothelial cells and the levels of keratan sulfate associated with them. The production of trypsin-like, chymotrypsin-like and chymoelastase-like protease activities cleaving N-Benzoyl-L-Phe-L-Val-L-Arg-p-nitroanilide, N-Succinyl-L-Ala-L-Ala-L-Pro-L-Phe-p-nitroanilide, and N-Succinyl-L-Ala-L-Ala-L-Pro-L-Leu-p-nitroanilide, respectively, was common among the strains examined.

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Uptake of chylomicron triglycerides by contracting skeletal muscle in rats. Many people, by means of consumption of seafood or other anthropogenic sources, are exposed to levels of methylmercury (MeHg) that are generally considered to be quite low, but that may nevertheless produce irreversible brain damage, particularly in unborn babies. Protease (0.54 U) from Aspergillus oryzae, prepared with or without OVA (75 micrograms), OVA alone, or saline, was administered intranasally to wild-type mice for 5 weeks.

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Mucinous adenocarcinoma of the renal pelvis in the horseshoe kidney: a case report As a result, these genetically diverse models represent a valuable resource for preclinical efficacy and drug discovery studies.

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In contrast, disrupting the post replication repair pathway only affected sensitivity towards m-AMSA. Low doses of fipronil produced greater effects when given for 14 days compared to a single dose. The effect of internally deposited plutonium-239 on the lysosomes of rat liver. The combination of enlarged LA and elevated estimated pulmonary pressure has a strong prognostic impact in patients suffering from HFpEF. For the patients and their families as well as the nursing staff it is necessary to get qualified at time for the outpatient situation already before dismission from hospital.

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Effect of acid etching duration on tensile bond strength of composite resin bonded to erbium:yttrium-aluminium-garnet laser-prepared dentine. Most recently, a growing number of preclinical studies have been reported on the therapeutic benefits of UTMD in the delivery of chemotherapeutic drugs to various malignant tumors, such as brain, liver, eyelid, pancreas, and breast tumors. Participation included mailed questionnaires containing the International Prostate Symptom Score, International Index of Erectile Function and the Dutch Survey of Intimate Relations (Nederlandse Relatie Vragenlijst) as well as uroflowmetry and cosmesis assessment using the Pediatric Penile Perception Score. Remediation of PCB-contaminated soil using a combination of mechanochemical method and thermal desorption.

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Schistosoma mansoni: ultrastructural observations on the small intestine of murine host. Proceedings: Small dense-cored vesicles in the cholinergic nerve terminals of the rat bladder. These equations describe the development of the electrical activity of the normal human brain, independent of cultural, ethnic, socioeconomic, or sex factors. Development of a preoperative criterion to select candidates for nerve-sparing radical prostatectomy at Kyoto University Hospital

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Enteral nutrition led to fewer postoperative complications than did parenteral feeding in gastrointestinal cancer. In the present phase-separating mixture with rods, the growth dynamics is examined in detail, and our simulations reveal a crossover from a rod-mobility-dependent to an independent regime. Multiple hereditary exostoses (MHE) is characterized by multiple benign projections of bone capped by cartilage, most numerous in metaphyses of long bones. While cases of AKI in urban areas of the developing world have similar characteristics to those in the developed world, AKI in rural regions commonly develops in response to a single disease and specific conditions (e.g.

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The initial presentation of the time-slowing suggestion did not result in improved performance accuracy. Moreover, the results of fluorescence spectra demonstrated that with the increase of GdnHCl concentration, the structure of protein had changed, but existence of crowding agents can make protein structure more stable. Spectroelectrochemical X-ray absorption data further reveal systematic spectral changes with successive oxidations from the cubane resting state. Reverse facial artery-submental artery island myocutaneous flap for reconstruction of oral and maxillofacial defects following cancer ablation (2) To compare the variables of gastric pH and volume with historical standards.

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Diagnostic criteria have been developed by the National Institute of Neurological Disorders and Stroke and the Society for PSP, Inc. Class II high-angle patients tended to have narrower and higher palates, while Class II low-angle patients were related to wider and more shallow palates.

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More than one malignant tumor at the same time with an accompanying relapse of a previous malignant tumor is a rare entity. Technique modifications are needed to improve correction precision. Relations between the ventrolateral thalamic nucleus and motor cortex and their possible role in the central organization of motor control. Biomimetic cross-linked polymersomes that exhibit a self-beating motion without any on-off switching are developed. Diffuse large-B cell lymphomas (DLBCL) and follicular lymphomas (FL) are the most represented subtypes among mature B-cell neoplasms and originate from malignant B lymphocytes.

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Non-HDL-C independently classifies risk levels of participants and is responsive to traditional rehabilitation. Typical between-session PFV differences (MAD) were between 3 and 4 delta, whereas the COR differences were as large as 12 delta.

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Nonparametric statistics were used to compare the demographic and clinical characteristics of the four groups. The nanosphere suspension culture method developed in this study may be useful for the mass production of recombinant proteins through large-scale suspension culture of anchorage-dependent animal cells. We provide in vivo and in vitro evidence that Fe-S clusters damaged by exposure to NO and H2O2 can be repaired by this new protein family, for which we propose the name repair of iron centers, or RIC, proteins.

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The significance of the memory deficits is discussed in relation to the hypothesis that childhood dyslexia is a double deficit of the graphemic-phonemic and graphemic-semantic reading routes. Treatment of severe refractory valvar pulmonary stenosis with primary transcatheter pulmonary valve implantation. The polymorphisms of two genes have recently been associated with complex forms of type 2 diabetes mellitus (T2DM): calpain 10 and peroxisome proliferator-activated receptor-gamma (PPARgamma).