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Implementation of a Monte Carlo dosimetry method for patient-specific internal emitter therapy. Measurements of intracellular calcium concentration showed that the application of bradykinin caused a transient increase in calcium concentration with similar characteristics to those observed in other endothelial cell preparations. Indeed, more recent studies have illustrated that this same Fas/FasL system may have negative contributions, perhaps serving as a novel mechanism of tumor escape of Fas-resistant subpopulations. Posttransplant maintenance therapy in multiple myeloma: the changing landscape. The effects of chronic corticosterone administration and adrenalectomy on the expression of brain dopamine receptors were studied in rats.

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It is then shown how the data from a molecular dynamics simulation can be used to construct a coarse-grained model for the heterogeneous bilayer that can predict the lateral organization and stability of rafts at up to millisecond time-scales. Polymorphism of DNA repair genes (XRCC1, XRCC3, XPC, XPD, XPA) in ethnic groups from Republic of Bashkortostan Clinical and follow-up data of 82 patients with cervical esophageal carcinoma undergone surgical treatment in Henan Provincial Cancer Hospital from Dec.

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Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies. Additionally, high PLAC8 expression was closely associated with a shorter overall survival time.

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Family physicians have the responsibility of diagnosing and adequately treating this. Eight patients, one man and seven women, were found to produce an autoantibody reaction with retina and optic nerve, including a novel 22-kDa neuronal antigen present within the retina and optic nerve. From January 2003 to April 2006, nasal mucociliary transport time was measured in 64 patients and specimens obtained by nasal scraping were examined by transmission electron microscope (TEM). Rapid and sensitive determination of sertraline in human plasma using gas chromatography-mass spectrometry.

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Calcifying fibrous pseudotumor is an extremely rare benign lesion that develops in the pleura. However, they can isomerize rather easily (the two possible isomerizations have a barrier of 16.79 and 7.17 kcal mol(-1)) to new more stable species. Peroxisome proliferator-activated receptors-gamma (PPARgamma) are ligand-inducible transcription factors of the nuclear hormone receptor superfamily. Influence of culture aeration on the cellulase activity of Thermobifida fusca. The two sub-sets did not differ on age of depression onset, family history of mood disorders, or depression severity and impairment.

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Percutaneous nephrostomy was performed after hemodialysis was initiated. Short intestinal segments were obtained from seven multiorgan cadaver donors.

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Single proximal anastomosis for multiple vein coronary artery bypasses in diseased ascending aorta. Isolation and identification of a novel aromatic amine mutagen produced by the Maillard reaction. The diagnostic sensitivity of ultrasonic examination for early liver cirrhosis is low.

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Collaborative efforts between treating specialists may improve implementation of evidence-based guidelines for OSS. The mechanism of its generation is not likely to be endosomal degradation of endocytosed material, as it is not chloroquine- or brefeldin-sensitive. An improvement in early transfer of this patient group to orthoplastic facilities has allowed all patients to be assessed and debrided within the recommended timeframe. Atherosclerosis is a chronic inflammatory disease of the arterial wall initiated by a variety of pro-atherogenic stimuli, such as modified epitopes of phospholipids. The purpose of this study was to evaluate the cationic trypsinogen gene in miniature schnauzers for possible mutations.

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These findings suggest that PepT1-mediated transport was not involved in the transepithelial transport of intact Val-Pro-Pro. Hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors reduces serum cholesterol in patients with high cholesterol blood levels including organ transplant recipients. Fenofibrate effectively reduces remnants, and small dense LDL, and increases HDL particle number in hypertriglyceridemic men - a nuclear magnetic resonance study. Lysostaphin was employed as a probe of the penetrability of the Staphylococcus aureus capsule. The decreased surface expression of class II molecules of the Main Histocompatibility Complex is both a marker of this state and a pathogenetic mechanism, as it decreases the antigen presentation capabilities of the mononuclear phagocytes.

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Early disorganization of the intermyofibrillar network and of the myofilaments, as well as dilatation of organelles, were observed by use of transmission electron microscopy. The CAMCOG-R subscores Memory and Executive Function have limited validity, and clinicians should be cautious in interpreting these in the absence of other neuropsychological measures or clinical information. The present NMR data, in combination with sequence comparisons between kappa light chains with and without protein L affinity, suggest that the amino acid substitutions at positions 9, 20, and/or 74 of the kappa light chains could crucially affect the interaction between protein L and the V(L) domain. Essential surgical skills include visuospatial and technical ability.

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Between September 2006 and December 2007, methods of EUS-BD were performed in four cases with inoperable pancreas head carcinoma. In order to elucidate the current status of IEBAM in Japan, in July 1996 a diagnostic determination system was established for high-risk screening for IEBAM. In this study, we evaluated the effects of FGF-1 in vitro and its production in vivo by use of an OA model. A 69-year-old woman who was a front-seat passenger developed disturbances of conduction with atrial fibrillation after blunt injury to the thorax.

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Dilatation of both benign and malignant strictures requires knowledge of the different types of dilators and the ability to adapt to different stricture characteristics. Based on the Stock-and-Flow simulation model of the US blood supply developed by Simonetti et al.

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The corresponding correlation coefficients are greater than 0.99. Familial-Environmental Risk Factors in South African Children With Attention-Deficit Hyperactivity Disorder (ADHD): A Case-Control Study.

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Although surgical endarterectomy remains the treatment of choice for carotid artery stenosis, stenting plays an important role as an alternative treatment modality, especially in high-risk patients. Using base substitution rates in intronic regions as a calibrator for neutral change, we found a strong avoidance of synonymous substitutions that disrupt predicted exonic splicing enhancers or create predicted exonic splicing silencers. Intravenous injection of narcotic stimulants affects many cellular functions relevant for the pathophysiological mechanisms of heart failure.

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Insulin-like signaling is the main mechanism of systemic nutrient sensing and mediates its growth-regulatory functions largely through the phosphatidylinositol 3-kinase (PI3K)/AKT protein kinase pathway. We compared the effects of a 12-week therapy with the AT(1)-receptor antagonist valsartan (Val) versus the beta-blocker metoprolol (Met) on arterial stiffness and endothelial function in mildly hypertensive patients at rest and during generalized sympathetic stimulation. Overall migratory activity of NSCs almost doubled after anodal tDCS.

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Point mutations within the eed gene that are responsible for severe embryonic development abnormalities abolished the transcriptional repressor activity of Eed. Conversely, the observed frequency of the genotype TC was significantly higher than expected. The primary endpoint, quantitative severity of myocardial perfusion abnormalities by PET, did not improve after 6 months of atorvastatin 80 mg daily compared to placebo.

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The heritability of overall shape variation was small, but some localized components depicting shape changes on distal wing regions showed medium to large heritabilities. Report on the 1st x-ray therapy case in Vienna (Leopold Freund, 1896)

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Among patients with oral cancer after radiation, ORN is an uncommon and dreaded complication. The heterozygous situation, named sickle cell trait, is perfectly well tolerated in contrast to homozygous or compound heterozygous forms, which lead to sickle cell anemia. This conclusion contrasts with previous experimental and theoretical correlations.

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A sensitive and specific EIA was developed to detect IgG anti-HEV activity in human sera. We present a case of an otherwise healthy 13-year-old male who presented with primary cutaneous alternariosis on his left ankle that responded to the use of topical econazole and oral itraconazole.

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Although complications in horses with fractures of the mandible and maxilla are common, long-term prognoses for functional and cosmetic outcome are favorable. We found little to no substantial difference in neighborhood characteristics between respondents and nonrespondents.

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In 150 gastric cancer patients, mRNA levels of BRCA1 and TS were assessed in plasma and paired tumor tissue. Opiate abstinence in the adult of many species, including humans, alters autonomic function and motor behavior, and induces a negative affective state.

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Sialyl Lewis(x) binds to selectins mediating neutrophil adherence to endothelium, thereby facilitating subsequent migration and tissue damage. Nanofibrous Silver-Coated Polymeric Scaffolds with Tunable Electrical Properties. Depressive and anxiety disorder diagnoses were assessed by using the Structured Clinical Interview for DSM-IV. Comparison of serum NO, TNF-alpha, IL-1beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus.

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We analysed their plans and progress towards achieving the TFAs pledge, comparing 2015 progress reports against their delivery plans. Light plays pivotal roles as an important environmental signal in plant growth and development. Labelled fibres and endings were also seen in the granule cell regions of anteroventral cochlear nucleus (AVCN) and the most dorsomedial parts of the dorsal cochlear nucleus (DCN). Determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in human urine. The test variables studied were learning and memory scores (from the Fuld Object-Memory Evaluation), verbal fluency, and conceptualization (the Similarities subtest of the WAIS-R).

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We define the thioredoxin-like fold using the structure consensus of thioredoxin homologs and consider all circular permutations of the fold. A number of experiments have shown that the magnitude of the associative priming effect increases substantially when there is a high proportion of associatively related pairs in the list when the stimulus-onset asynchrony (SOA) between prime and target is long (more than 400 ms). Scleroderma and other diseases associated with cutaneous sclerosis. The results indicated that the incidence of fentanyl-induced cough increased, and the onset time decreased, with the increasing dose of fentanyl. The mechanism of an immature secretion phenotype of a highly frequent naturally occurring missense mutation at codon 97 of human hepatitis B virus core antigen.

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This may in part contribute to the hypertriglyceridemia, hypocholesterolemia, and hypophospholipidemia noted after burn injury. Therefore, it could be helpful and suitable to administer artesunate in the context of cerebral malaria, especially in young children. After establishing a baseline understanding of some of the factors that influence and shape family end of life communication, empirical research centered on the communication tendencies of nationally-recognized palliative care clinicians is presented.

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Abdominal hernia repair with implantation of synthetic meshes using the sublay technique has resulted in low recurrence rates and high patient satisfaction. A milestone of this ability is reached around the age of 4, when children start understanding that others can have false beliefs about the world.

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Rhodococcus equi pericarditis in a patient living with HIV/AIDS. On the basis of these results we propose a framework for a new class of neural network models for the spatial RF organizations of prototypic V4 neurons.

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In the absence of a large-scale, prospective, naturalistic, pharmacoeconomic study, an alternative indication of product superiority can be derived from a continuum of different types of studies (from basic science to clinical trials to retrospective pharmacoeconomic analysis) conducted in a variety of patient care settings. Following injection, L6 cells either fused with each other to form homotypic fibers or fused with host muscle cells to form heterotypic fibers. The objective of this study was to determine the effects of epinephrine and norepinephrine on mucosal villous blood flow in a normotensive model of endotoxemia. Nuclear localization and replication activities of most of these mutations are enhanced or restored by mutations in the NES.

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Prophylactic agents are efficacious for prevention of HBV reactivation in HCC patients receiving TACE. They project to horizontal cells and bipolar cells via a glutamatergic feed forward pathway. Mild, transient alanine aminotransferase (ALT) elevations were seen in Phase I studies of caspofungin and cyclosporin A (CsA). Ectopic expression of platelet integrin alphaIIb beta3 in tumor cells from various species and histological origin.

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The purpose in the present study was to determine whether the commercial combination of trimethoprim (TMP) and sulfadiazine (SDZ) tribrissen (TRI) was more effective than either of the components for treating experimentally induced infection of Streptococcus zooepidemicus. Domains and items for the SS-QOL were developed from patient interviews.

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An early intervention with rituximab might affect the disease course in pediatric NMO-IgG-positive NMOSDs. Absence of blood flow in the twisted pedicle and visualization of the flow in the artery alone are predictive of nonviability of the ovary. This investigation examined the relationships among Step 1 performance, preparation method, and academic achievement in medical school. The data are discussed in terms of the interfacial properties presented by the polySMBA surfaces.

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Subjects were interviewed individually regarding the experience of chewing areca quid and the evidence of lifetime areca quid use disorder. Few such studies have been conducted, however, that rely on very old source records, perhaps because of concern that identification and location of a cohort based on very old records would not be feasible.

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There is a need to address this hypothesis directly in studies with reliable measurements of both homocysteine and blood pressure. This study was to explore effect of cFLIP ASODN on apoptosis of human gastric cancer cell line BGC823. Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. The LION study is a 12-month pragmatic single-blind multi-site cluster randomised controlled trial.

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The potential utility of the SIBS interview for assessing the role of siblings in the development of antisocial behavior is discussed. Modifications of the hand held clip and optimization of ablation parameters would likely improve the success rate of this procedure. Inflammatory and autoimmune manifestations in X-linked carriers of chronic granulomatous disease in the United Kingdom.

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Neurotoxicity associated with calcineurin inhibitors cyclosporin A and tacrolimus is established. (32)P-Labeled SV40 DNA was treated sequentially with restricting endonucleases EcoRI and Hpa I, and the resulting four fragments of DNA were separated by gel electrophoresis.

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In this study, a facile and novel strategy was developed to fabricate magnetite/graphene oxide/chitosan (Fe3O4/GO/CS) composite, and the composite was used as a magnetic adsorbent for the enrichment of protein, and followed by matrix-assisted laser desorption ionization mass spectrometry (MALDI-TOF MS) analysis. Studies have suggested that connective tissue alterations play a role in the formation of both diverticulosis and abdominal wall hernia.

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Analysis of expression profiling of sHsp genes revealed that these genes are differentially expressed under stress and at different stages in the life cycle of rice plant. All Avon Valley outbreak isolates shared the same multilocus sequence type (ST-284), which has not been identified outside this region. Few studies have investigated dietary patterns among French adults. Longitudinal changes in femur bone mineral density after spinal cord injury: effects of slice placement and peel method. Disturbed morphogenesis of cardiac outflow tract and increased rate of aortic arch anomalies in the offspring of diabetic rats.

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Primary study endpoints included left ventricular volume and function. Amino acids, peptides and proteins could be analyzed in ionic liquids after addition of matrix substances. To isolate release from glycinergic amacrine cells, we used either bicuculline, a GABAA receptor antagonist, or picrotoxin, a GABAA and GABAC receptor antagonist. Tests of executive functioning predict scores on the MacAndrew Alcoholism Scale.

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Moreover, both Th2 cells and the effector cells usually present in the areas of allergic inflammation (basophils, mast cells, and eosinophils) express chemoattractant receptors, such as CCR3, CCR4, CCR8 and CRTH2. These assays are also important in determining proper dosage for gonadotrophin and clomiphene treatment. Polylactide-co-glycolide (PLG) microparticles modify the immune response to DNA vaccination. While scepticism towards this type of non-toxic medical intervention is mounting, such patient-specific treatments might yet see the light of day through better designed clinical trials. Neural transplantation of human neuroteratocarcinoma (hNT) neurons into ischemic rats.