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Doxtran (Diclofenac)
+ BONUS
 
Diclofenac

Studies containing Doxtran pharmacokinetic data were identified during a Cochrane systematic review, and authors were asked to provide raw data. In this study, exposure and ecotoxicity data of six human pharmaceuticals (carbamazepine, clofibric acid, Doxtran, ofloxacin, propranolol, and sulfamethoxazole) were collected, including our own experimental data and literature data.

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Transdermal Doxtran is used to treat short-term pain due to minor strains, sprains, and bruises in adults and children 6 years of age and older. Doxtran is in a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by stopping the body's production of a substance that causes pain.

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We found that mianserin, a serotonin receptor antagonist used as an antidepressant in humans, can increase C. Ultrasound and CT changes of liver parenchyma in acute schistosomiasis.

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Vascular changes of the gastric fornix following surgical interventions at the pancreas The four disulfide bonds required for stabilization of the nsLTP2 structure show a different pattern of cysteine pairing compared with nsLTP1.

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The V91G mutation weakens the interaction of both apo- and holo-D-CaM with this binding region, and decreases the enhancement of the calcium-binding affinity of CaM that is detectable in the presence of the RyR target peptide. Emotion dysregulation in the intergenerational transmission of romantic relationship conflict. Although there were significant racial differences in disability, there were no significant racial differences among these MS residents in the use of various therapies provided by qualified therapists. We further show that RBR1 is itself targeted to DNA break sites in a CDKB1 activity-dependent manner and partially co-localizes with RAD51 at damage sites. Thus, although post-translational amino acid isomerization appears to have no strong specificity for the chemical nature of the amino acid side chain, the few peptides where this modification has been established suggest that there may be favored positions near the N or C terminus that are preferential sites for isomerization to a D-amino acid.

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Risk factors, clinical syndromes, and possible indirect effects of CRV infections are discussed. We isolated seven polymorphic microsatellite loci from a ground beetle (Bembidion atrocaeruleum, Coleoptera, Carabidae (Stephens, 1826)) associated with naturally and regularly disturbed floodplain habitat in northwest Europe.

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Prothrombin complex concentrate (PCC) can substantially shorten the time needed to reverse antivitamin K oral anticoagulant therapy (OAT). For the first time human lymphocyte antigens (HLA) were determined, pointing to a genetic predisposition. Current drug withdrawal strategy in prolactinoma patients treated with cabergoline: a systematic review and meta-analysis. The percentage of serotonin released from platelets adhered on surface-modified PUs was increased with increase of platelet adhesion. A male at age 66 was suffered from progressive low back pain associated with hypesthesia in his right leg.

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converted food more efficiently into body mass when their biological mother was dark pheomelanic. Cytomegalovirus-associated haemophagocytic syndrome and acute renal failure in a patient with chronic lymphocytic leukaemia All alternatively spliced forms of Peg5 were expressed only from the paternal allele, confirmed using DNA polymorphism in a subinterspecific cross. However, the concentration of DAB needed for inhibition of glycogen shunt activity, i.e. Theoretical evaluation of parameters of equally probable safe single-step hypobaric decompression

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Elucidating the molecular defect(s) in these pedigrees will likely be relevant for understanding sporadic MPD pathogenesis. The characteristic dermonecrotic lesion results from the direct effects of the venom on the cellular and basal membrane components, as well as the extracellular matrix. Mesna ESD for SESCCs is a safe procedure with the potential to facilitate esophageal ESD.

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In conducting studies based on OCT as single examination, it should be clearly defined how long fibrotic lesions or lesions with pigment epithelial detachment should be re-treated. PATH hosted a workshop on October 14 and 15, 2013 in Washington, DC to solicit expert opinions on the potential merits and challenges of developing combined enterotoxigenic Escherichia coli (ETEC) and Shigella vaccine products to benefit children in developing countries. We have previously found that retinoic acid stimulates the expression of protein kinase C alpha (PKC) in B16 mouse melanoma cells. In addition, ESB could inhibit STAT-3 signaling, down-regulate Mcl-1 and Bcl-2 expressions, and induce degradation/activation of apoptosis-related proteins Caspase-3 and Caspase-9 and PARP degradation in a dose-dependent manner. Our findings suggest clinical symptoms as linked with heavier body weight, wider neck circumference, elevated blood pressure, and shorter SWS.

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These new approaches have been used in order to resolve the complex effects of diseases, conditions, environmental factors, and genes in relation to the protective role of HDL but high-throughput methods are still needed for large-scale epidemiological studies. We suggested that the continuous translocation of endotoxin from Gram-negative bacterial overgrowth during bowel rest and total parenteral nutrition (TPN) causes the release of tumor necrosis factor (TNF), resulting in liver damage and hepatic dysfunction. To investigate the effect of practice paradigms that varied treadmill speed during step training with body weight support in subjects with chronic hemiparesis after stroke. The expression of midkine in germ cell tumors was significantly lower than in epithelial tumors, whereas expression in malignant epithelial tumors was significantly higher than in benign ones. The assessment of levels of physical activity relies upon suitable measurement tools.

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Management of unruptured intracranial aneurysm in Japan: a Markovian decision analysis with utility measurements based on the Glasgow Outcome Scale. By contrast, overexpression of the dominant negative AMPKalpha2 mutant in muscle markedly suppressed both AICAR-induced glucose uptake and AMPK activation, although insulin-induced uptake was unaffected. Types of adaptive sampling designs include ordinary sequential sampling, adaptive allocation in stratified sampling, adaptive cluster sampling, and optimal model-based designs.

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To study the chemical constituents from Salvia roborowskii Maxim. Then the optimal scheduling of a vessel disruptive agent in combination with a cytotoxic drug is considered as an optimal control problem. We discuss reasons for this drawback and we offer several recommendations. However, these studies lacked sufficient epidemiological information to confirm such an occurrence.

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voriconazole and posaconazole) therapy will allow survival of most patients into adulthood. The prevalence of diabetic retinopathy at the baseline, the incidence of sight threatening diabetic retinopathy (STDR) in the next two rounds of screenings, and the long-term visual outcome are described. Once-daily oral BAY 57-1293 was significantly more effective than valacyclovir and as effective as twice a day topical trifluridine. Given the known risk of recurrence in patients with persistent tumor enhancement after UAE, it is concluded that tris-acryl gelatin microspheres should be the preferred agent for UAE at this time.

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Oxidative stress injury associated with 8-isoprostane production is not involved in the pathogenesis of FDM-affected PWC dogs. Catch-up growth during tocilizumab therapy for systemic juvenile idiopathic arthritis: results from a phase III trial. First, suitable organs for xenotransplantation from animals to humans may be developed, or second, as described in this report, application of tissue engineering may result in development of a range of devices to aid care of patients with renal failure.

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Here, we investigate how the presence of endoplasmic reticulum (ER) in dendritic spines of CA1 pyramidal neurons affects postsynaptic signaling. NADH oxidase, but not succinoxidase, could be restored in membrane preparations by the addition of menadione to the reaction mixture. Both CQ and PD98059, a MEK1 inhibitor, reduced luciferase reporter activity driven by human TNF promoter sequences. We characterized the normal canine prostate in comparison to the normal human prostate. Our results also support the neuropathic hypothesis of uraemic pruritus.

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One patient was excluded on pathology review (elements of endodermal sinus tumor were present) developed recurrent tumor and died despite further therapy. According to our immunohistochemical study, BASP1 and MARCKS are specifically distributed in the tissues studied. Therefore, we report here a rare case of the radial artery which is very strange but potentially valuable for the clinical practice: it arises at a right angle from the brachial artery and passes behind the biceps brachii tendon. This strategy could limit the risk of excessive myometrial response (hyperkinesia or hypertonia) and thus improve fetal tolerance. In these cells, c-MET was detectable and constantly expressed for at least six days of culture.

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Five stroke patients and 16 normal controls underwent Tc-99m hexamethylpropyleneamine-oxime brain SPECT and 1H MRSI at 4.1 T. In addition, the localization of HGF mRNA and c-met protein was analyzed using in situ hybridization and immunohistochemical staining, respectively. Mondini dysplasia with CSF fistula must be included as a possible diagnosis when faced with a patient with recurrent bacterial meningoencephalitis. The above adaptations were best seen in the young and in the animals trained at thermoneutral temperatures.

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The risk for teratogenicity of valproate (VPA) increases in a dose- or concentration-dependent manner. In vitro desaturation of 1-14C linoleic acid in Novikoff hepatoma. This result indicates that binding of the nucleotide in the active site induces an allosteric conformational change within the central threefold channel of the homotrimer exclusively in the eukaryotic enzyme.

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Rs2289669 was genotyped, using Sequenom, in 291 participants receiving 48 weeks of metformin monotherapy. Neutrophil recruitment into tissues is a multistep process involving sequential engagement of adhesion molecules.

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Administration of alpha G-Rutin (50 mumol as rutin/kg) by gastric intubation 30 min after i.p. The expression dynamics of specific mRNA contains substantial information on the intracellular milieu. Hyperinfection syndrome with Strongyloides stercoralis is not uncommon in immunocompromised patients. Binding of basic amphipathic peptides to neutral phospholipid membranes: a thermodynamic study applied to dansyl-labeled melittin and substance P analogues. To ensure the CDM program appropriately assists patients to receive optimal care, further review of the CDM program within the scope of dietetics is required.

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Aging caused an increase of the distance between the pupil centre and the lower eyelid of about 1 mm in men, and 0.5 mm in women. In vitro assays revealed that Egr-1 displaces Sp1 from its binding site in IRE-II. Evaluation of stability of titanium and hydroxyapatite-coated osseointegrated dental implants: a pilot study. Intracellular beta-tubulin/chaperonin containing TCP1-beta complex serves as a novel chemotherapeutic target against drug-resistant tumors. Role of aggregated human growth hormone (hGH) in development of antibodies to hGH.

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We demonstrated that the calibration curve for all studied molecules is universal and linear within 0.1 to 1.2mg protein content range. The elevated hydrophilicity and excellent water transport abilities of plant tissues allow cell expansion over prolonged periods of culture. With combined fluorescent in situ hybridization and immunofluorescence, TNF-alpha-expressing cells were frequently identified as CD68-positive macrophages within perivascular lesions.

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Sixty patients were enrolled and randomized to receive either the SR71 stem or an all-metal stem (Stability). Blunted autonomic reactivity to pharmacological panic challenge under long-term escitalopram treatment in healthy men. Fibrinolysis remains problematic during thoracic aortic aneurysm surgery. No differences were detected in osmotic fragility, GSH concentration and PK activity between the two groups but 2,3DPG concentration and G6PD activity were statistically significantly higher in the diabetic group. Magnetic resonance imaging should be considered in the evaluation of patients with cGVHD suspected of having subcutaneous or fascial involvement.

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The increase in the aqueous flare intensity in this patient indicates that the function of the blood-aqueous barrier might have been affected in crystalline retinopathy. Depending on loop length the top prediction varies between 1.06 A RMSD for three-residue loops and 3.72 A RMSD for eight-residue loops. Ventilator-associated pneumonia as a quality indicator for patient safety? Of the four types of health care visits compared, dentate adults with diabetes were least likely to have had a dental care visit in the preceding year. Potential association between calcified thoracic lymphadenopathy due to previous Histoplasma capsulatum infection and pulmonary Mycobacterium avium complex disease.

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Enrollees in managed care plans spontaneously discussed trust and distrust in individuals and institutions during conversations about their insurance expectations and experiences. Despite we know lots of environmental risk factors and we made important advances in the prevention and treatment of mentioned diseases, our knowledge about the pathogenic linkage between genetic predisposition and cardiovascular diseases is still very little.

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Fifty-five women, aged 21 to 58, 27 of whom were married participated in two psychophysiological laboratory sessions and completed a questionnaire. The European Public Health programme may be an opportunity to realize these goals. CCL3 contributes to the OB/OC imbalance by inhibiting OB differentiation and function in MBD. microRNA-126 delivered by microparticles mediates intercellular signal transmission

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In this paper, we examine the effect of the dose level of the bacterial endoparasite Pasteuria ramosa on the infection rate of its host, the water flea Daphnia magna. A study of the viability of obtaining a generic animation of the foot while walking for the virtual testing of footwear using dorsal pressures. Nanomaterials have shown great potential in tumor therapy, due to their unique properties, including passive targeting, hyperthermia effects, and tumor-specific inhibition.

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The accuracy of border detection was validated against manual border tracing on FDG-PET images, simulated Tl-201-SPECT images where the true underlying borders were known, and actual Tl-201-SPECT images. Anatomical reconstruction of the distal tibiofibular ligaments with the peroneus brevis tendon provides stability and recreates the biomechanical properties of an intact syndesmosis. Since then, significant progress especially in the development of vaccines in novel continuous cell lines of mammalian origin as well as in insect cells has been made and consequently there is an increasing need for the re-evaluation of existing criteria for the acceptability of such cell lines. Accordingly, FAK, EZH2 and H3K27me3 were concomitantly upregulated in human HCCs compared to non-tumor livers. There has been a great interest worldwide in developing a reliable and widely applicable assay of the hormone in biological fluids.

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Estrogens and glucocorticoids inhibit and prostaglandin E2 stimulates the promoter of human CRH gene in transfected human endometrial cells, suggesting that endometrial CRH gene expression is under the control of these agents. Although the 3 most distinctive gene-expression modules represented the signatures of 2 different subgroups of HCC, most of the cell lines shared many coexpressed genes. Current concepts of respiratory insufficiency syndromes after fracture.

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This study was conducted on 92 patients who underwent unilateral MITLIF between 2006 and 2013, had been tracked with a follow-up for at least 1 year, and had been assessed by pre- and postoperative computed tomography (CT). Assessment of inner dynein arm structure and possible function in ciliary and flagellar axonemes. Lung tissue, peritoneal fluid, and blood were collected at 1, 3, 6, and 18 h after surgery for subsequent analysis. Hyaluronate inhibition of chondrogenesis: antagonism of thyroxine, growth hormone, and calcitonin. This cluster of genes may represent the vestiges of an ancient coadapted gene complex in controlling mating behavior.

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Occupational accident and disease claims, work-related stress and job satisfaction of physiotherapists. elegans ina-1 alpha integrin mutants provides the first genetic evidence that migrating neurons require integrins.

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The only common element found in most conformations of the active peptides was a helical character of fragment 8-13, which allowed the side chains of basic amino acid residues to be exposed to the outside of the molecule and probably to interact with the ORL1 receptor. From our histologic and biomechanical studies in animals, a superior healing process and stronger healing strength can be achieved when periosteum is sutured onto the tendon inserted within a bone tunnel. The main outcomes were the rates of emergency department (ED) visits and hospitalizations by quartile of PGH physical and mental health scores.

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A 17-month-old girl underwent successful single-stage anatomic repair using a technique of ventricular septal defect translocation for complete atrioventricular canal, double-outlet right ventricle, pulmonary stenosis, cor triatriatum, and left superior vena cava to an unroofed coronary sinus. Participation of Campylobacter jejuni flagellar epitopes in cellular adhesion The changes in gene expression profile were observed at time points (36 hours) using real-time PCR-based gene screening with categorized primer sets. A sample of 193 subjects drawn from the New South Wales Fire Brigade was studied to examine the prevalence of chronic respiratory disease and impairment of respiratory function. Drawing on data in relation to these two programs, the present study highlights issues impacting dental service provision.

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A similar observation was made with mutants of Glu22, a residue that is highly conserved among several lipid II-binding lantibiotics such as mersacidin. Our laboratory has reported that mice that express a dominant negative form of transforming growth factor beta receptor restricted to T cells (dnTGFbetaRII) develop an inflammatory biliary ductular disease with elevated serum levels of interleukin (IL)-12p40 and other proinflammatory cytokines and antimitochondrial autoantibodies (AMAs) closely resembling human primary biliary cirrhosis (PBC). Direct binding of carrageenan onto NK cells was also demonstrated. Hypoxia is a practically useful means of increasing physiological strain during BWS rehabilitation.

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Special pleochroism in the far-infrared spectra of ferroelectric triglycine sulfate. This global increase in slow wave activity power was positively correlated with the frequency of secondarily generalized seizures in the 3-5 days preceding the recordings. The results indicate that the PLT quality after storage for 7 days is well preserved, although activation of PLTs occurs during storage as assessed by in vitro tests. Preparation of Highly Biocompatible ZnSe Quantum Dots Using a New Source of Acetyl Cysteine as Capping Agent.

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An ecosystem services approach to the ecological effects of salvage logging: valuation of seed dispersal. To determine the relationship between serum lipid levels and the incidence of coronary events in older Japanese hypercholesterolemic patients without prior coronary heart disease (CHD).

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The test statistic, denoted as Cg, is obtained by calculating the Pearson chi2 statistic where the estimated expected frequencies are the sum of the model-based estimated logistic probabilities. In AV17h1-infected mice fed on a high fat cholic acid (HFCA) diet, mRNA expression and activity of both the endogenous and adenovirus (human) 7alpha-hydroxylase were repressed. The control group consisted of 724 consecutive PCI patients receiving only aspirin pre-treatment. In standard clinical practice laboratory monitoring is not routinely performed, with drug dosing assessed by clinical inspection of the extracorporeal circuit, and the time for fistula needle sites to stop bleeding.

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However, even though CAM doctors preferentially apply COM therapies, cardiovascular patients treated by CAM doctors are more likely to be satisfied with the overall treatment outcome, possibly because of the longer and better patient-practitioner interaction. We conclude that there are genes on chromosome 22 that are involved in sex determination. Disruption of the drebrin/EB3 pathway using BTP2, a small molecule inhibitor of drebrin binding to actin filaments, reduced the invasion of prostate cancer cell lines in 3D in vitro assays. The very high level of conservation of the H2A.F/Z family of variant histones suggests that the equivalent fusion protein construct should function equally well in a wide range of organisms. The more distal attachment of the fibularis brevis in this case is a regression in evolution.

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The aim of this study was to assess the sensitivity of the LDAEP to acute augmentation in central serotonergic neurotransmission in humans. The loss of L-selectin was due to cleavage and shedding of the molecule from the cell surface, as quantitated clarithromycin antibiotic breastfeeding by the soluble form of L-selectin in cell-free supernatants.

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Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center. Radiotherapeutic factors in the management of cervical-basal chordomas and chondrosarcomas. We choose to compare three commercially available OST-HMDs, which are representatives of currently available head-mounted display technologies. Simulation of human aldactazide dosage forms ppt thermoregulation during water immersion: application to an aircraft cabin water-spray system. An inherited form of high cholesterol--familial hypercholesterolemia--demands serious action.

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The role of mammalian intestinal bacteria in the reductive metabolism of zonisamide. Recombinant caspase-3 can also cleave eukaryotic initiation factor 4G to yield the 76 kDa fragment both in cell extracts and when the eukaryotic initiation factor 4G is presented in a purified eukaryotic initiation factor 4F complex. Recurrent liver disease, especially viral hepatitis, and CMV infection appear to pose significant risks to mother and offspring, respectively, although the magnitude of the risks is unknown. Here we report that naltrindole, which has been used as a classic delta opioid antagonist, inhibited growth and induced apoptosis in the three characteristic SCLC cell lines, NCI-H69, NCI-H345, and NCI-H510. Male institute of cloze test english tips for children Cancer Research mice received 5 days of TPN followed by 0 to 4 days of chow.

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Data were analyzed using the framework of ethnomethodology to indicate the methods nursing assistants used to make sense of lisinopril and hydrochlorothiazide tablets their interactions with demented residents. To study the protective effects of isoflavone extract from soybean cake against the UVB-induced skin damage. For each question, a bibliographic review was performed and used to build a structured and standardized answer, based on the best available scientific and clinical evidence. We investigated whether there are differences among health- old people and old people suffering from lung cancer at different stages of disease in the 24-hour secretory profiles of GH und IGF-1.

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Information mathematical simulation estocin ointment for bruises of resuscitation activity of a multiprofile hospital will help get a detailed characterization of patients and of the activity of resuscitation wards, help assess the contribution of physicians and paramedics and the level of mastering present-day medical technologies by them. We conducted a search of the MEDLINE database for clinical studies evaluating the effect of glutamate-modulating drugs in OCD. In this study, we propose an innovative integrated H-G scheme combining human health risk assessment and geographical detector methods that was based on geographical information system technology and validated its feasibility in a renewable resource industrial park in mainland China. Eight participants reviewed a 60-minute training module outlining 3 different i-SCAN modes demonstrating the entire spectrum of inflammatory mucosal and vascular changes in UC. In liver fibrosis, activated hepatic stellate cells (HSC) play a major role in the deposition of excess extracellular matrix, including fibrillar collagens type I and type III.

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