Cofac is a medicine that reduces inflammation and pain.

It's used to treat aches and pains, as well as problems with joints, muscles and bones. These include:

• rheumatoid arthritis, osteoarthritis and gout
• sprains and strains in muscles and ligaments
• back pain
• ankylosing spondylitis - this causes inflammation of the spine and other parts of the body
• toothache
• migraine

Cofac comes as tablets, capsules and suppositories. These are available on prescription only.

It can also be given as an injection or as eyedrops. These are usually only given in hospital.

Cofac gel and plasters for joint pain are available to buy from pharmacies.

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Imiglucerase, the recombinantly produced enzyme, is gradually replacing the human placental derived alglucerase in the treatment of gaucher patients. Growth/differentiation factor-15(GDF-15) is a divergent TGF-beta family member that is expressed following liver injury and carcinogen exposure.

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New York investigators have found, to their surprise, that high incidence of HCV did not necessarily mean high rates of HIV. The strength of Atlantic meridional overturning circulation is believed to affect the climate over glacial-interglacial and millennial timescales. Our results show promise for enhanced QUS-based assessment of osteoporosis. On T1-weighted magnetic resonance imaging studies, after frequency-selective fat saturation, an optic nerve mass was detected at the level of the optic canal with signal characteristics suggesting the diagnosis of optic nerve lipoma. Complete clearing of the treated areas was achieved in five patients with palmoplantar psoriasis, three of whom had the pustular variety.

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In adult and kitten antrum isolated smooth muscle cell contraction, levels of 1,2-diacylglycerol (DAG) and IP3 were assessed in response to cholecystokinin (CCK). Plasma testosterone, androstenedione and urinary 17-oxosteroids in hirsutism. These findings support postulated associations between infrequent fresh fruit consumption and the prevalence of frequent or severe asthma symptoms in adults. The pectoralis paddle myocutaneous flap is extremely dependable and provides an added advantage of covering the vital structures of the neck with adequate length without excessive bulk. Brassinosteroids (BRs) are steroid phytohormones required for plant growth and development.

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The bioinformatics approach has been tested on a set of SNPs that are reported to have a regulatory function, as well as background SNPs. Although approaches to health information sharing emphasize consent, public opinion also emphasizes purpose, which suggests a need to focus more attention on the social value of information use.

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