Bisocard is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet

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Agents that block interleukin-1 or tumor necrosis factor-alpha appear similarly effective in slowing radiographic progression in patients with active rheumatoid arthritis. Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene. ILC2s have been primarily identified at environmental-mucosal interfaces and can be activated quickly by environmental antigens and pathogens to produce large quantities of IL-5 and IL-13. The dedifferentiated cells can then differentiate to reconstitute the lost tissues.

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The patient underwent magnetic resonance imaging (MRI) testing that revealed an enhancing mass in the left temporal lobe. Protein phosphorylation and dephosphorylation are believed to play key roles in regulation of sperm motility. This article describes a collaborative, culturally appropriate, holistic, and ecological lay health advisor program--the Latino Health Advocacy Program. The staging of this component was modified by dividing stage 2SN into 2SN (early) and 2SN (late).

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Prematurity continues to be the leading cause of neonatal death and developmental disability, highlighting the importance of identifying potential predictors of prematurity as well as interventions that can be linked to the predictors. Characteristics of short-period blazed fiber Bragg gratings for use as macro-bending sensors. Reconstruction after resection of pelvic sarcomas while preserving function of the hip and limb can be extremely challenging especially in children where there are issues of growth potential and limb-length discrepancies. Experimentally, this process can be observed in different settings, such as in laser arrays and lattices of semiconductor optical amplifiers. To compare different approaches to address ceiling effects when predicting EQ-5D index scores from the 10 subscales of the MOS-HIV Health Survey.

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The reversal potentials for the slow HPs and the slow DPs were recorded at the same membrane potential (-11 to approximately -13 mV). The ability to produce NO by intestinal microflora or probiotic bacteria is unknown. The mercury concentrations recorded from blood, kidneys, and urine suggested that metallic mercury was properly absorbed through the skin. The methodology for local adaptation of CPGs to meet the local needs and resources are explained in this review.

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Effect of angiotensin converting enzyme inhibition on renal autoregulation. Light and electron microscopical studies on localization and differentiation of activities of nucleoside phosphatase in the Schweigger-Seidel capillary envelopes in the spleen of swine

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Description of paclitaxel resistance-associated genes in ovarian and breast cancer cell lines. Together with the strong fixation of the acyl acceptor L-malate, the acquisition of this reaction mechanism favours transacylation over hydrolysis in AtSMT catalysis.

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Surgical guidelines based on the constant and variable features of the macro- and microcirculation are presented, which if carefully observed are helpful in avoiding the dread complication of postoperative paraplegia. The follow-up recheck period is 2 years in the first, 9 months in the second and I day in the third case. Alterations in the endocrine milieu at puberty may influence cortisol pharmacokinetics and, consequently, the handling of hydrocortisone used as replacement therapy.

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Participants also worried about the future regarding long-term medication use and drug dependency, and if a medicine proved to be ineffective, about the risks of future treatments and running out of options. A mathematical model, based on ASM1 model and implemented in AQUASIM was developed and used for simulating the treatment plant of Garmerwolde. Reduction of peridural fibrosis after lumbar laminotomy and discectomy in dogs by a resorbable gel (ADCON-L). The results are stored in files for further statistical analysis. A 29-year-old pregnant woman was hospitalized due to severe dyspnea.

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The authors believe that this relatively new technique represents an advance in the management of complex and large cranial defects, but seems less suitable for simple defects because of cost-intensive techniques. Apoptosis was assessed morphologically and also biochemically by measuring caspase activity and the mitochondrial membrane potential.

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Differential satiating effects of fats in the small intestine of obesity-resistant and obesity-prone rats. UDP-glucose pyrophosphorylase synthesis in myxamoebae of Dictyostelium discoideum. CE immunoassay with enhanced chemiluminescence detection of erythropoietin using silica dioxide nanoparticles as pseudostationary phase. Joint aspiration under biplane fluoroscopic control and culture of the aspirated material is indicated in establishing the specific etiologic agent which is Staphylococcus aureus in most cases. Secretory carcinoma (SC) is a rare variant of breast carcinoma, which was first described in children and adolescents but it can occur at all ages.

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Immunohistochemical staining was useful for diagnosis and differential diagnosis. Radiographic signs in post pneumonectomy bronchopleural fistula. Food insecurity was measured with the Radimer/Cornell questionnaire.

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We show how a small research project conducted in collaboration with five Indigenous women developed into a significant research partnership and resulted in a better understanding of the issues that must be addressed by research in future. We used logistic regression analysis to estimate associations between HIV-1 and HIV-2 infection and the risk of cervical neoplasia.

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The kinetocardiographic study of the diastolic structure demonstrated its consistent changes. This study provides evidence that the growth-factor complex is required throughout follicle development, and also for continued maintenance of the corpus luteum (CL) in the mature animal. Inflammatory Response and Barrier Dysfunction by Different e-Cigarette Flavoring Chemicals Identified by Gas Chromatography-Mass Spectrometry in e-Liquids and e-Vapors on Human Lung Epithelial Cells and Fibroblasts. The treatment of choice for MS disorders in Western medicine is the administration of nonsteroidal anti-inflammatory (NSAID) agents.

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Effect of endurance training on blood lactate clearance after maximal exercise. To document the influence of IL-6 on PG cells growth in vivo through the strategy of the transfection of expression vector inserted antisense IL-6 cDNA. Maternal age effects on longevity in Drosophila melanogaster populations of different origin. This study reports the first development of a network analysis approach to inform countries on their transgressor and detector profiles as a user-friendly aid for the adoption of the Beijing Declaration.

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To evaluate the diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) features of cervical spinal cord astrocytoma. Lysosomal enzymes of the catabolism of connective tissue basal substance in the newborn adaptation period Thus, an intraluminal administration of antisense ODN directed to a specific cell cycle regulatory gene can inhibit neointimal formation after cardiac transplantation.

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There is a high incidence of occult regional disease even in early-stage supraglottic squamous cell carcinoma of the larynx. Only complete surgical staging accurately depicts the extent of this disease. Computer use patterns associated with upper extremity musculoskeletal symptoms. VEGF-receptor tyrosine kinases, VEGF-R1 (flt-1) and VEGF-R2 (flk-1), are induced in a tumour stage dependent manner during glioma progression and are exclusively expressed in tumour vascular endothelial cells.

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Intracutaneous rather than epicutaneous testing is the indicated route and may be related to the route of sensitization. With increased use comes increased potential for misuse and abuse.

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There were an estimated 426,010 DAWN-defined visits involving prescription opioid use in 2011. This article aims to review the current understanding of the etiologies and the multiple pathogenetic pathways that are likely to lead to the autistic phenotype. During the past decade, considerable progress has been achieved in defining new prognostic markers, diagnostic parameters, and treatment options.

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Improved outcome after lumbar microdiscectomy in patients shown their excised disc fragments: a prospective, double blind, randomised, controlled trial. Improved liquid-chromatographic assay of urinary catecholamines.

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This critical review provides a concise overview of the most important syntheses of porphycenes, as well as those of various functionalized derivatives and heteroatom containing analogues. Oxidative phosphorylation and steady-state ATPase activity of purified F1 were severely impaired by both mutations. Furthermore, both parameters were significantly higher at the 1.5-hour and 3-hour erythrocyte samples when compared to initial values in the FFLT group.

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Increasing prevalence of antibiotic resistance and multi drug resistance among uropathogens. Soluble triggering receptor expressed on myeloid cells-1 levels were significantly lower in non-survivors at both time points. Reaction rates and dissolution mechanisms of quartz as a function of pH.

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BIS values also positively correlated with activity in brainstem and thalami, both structures known to be involved in arousal and wakefulness. Diagnosis of congenital infection in the neonate is dependent on the appropriate laboratory techniques being used. To investigate whether intensive induction therapy followed by triple-tandem cycles of high-dose therapy with peripheral-blood stem-cell rescue and local irradiation will improve event-free survival for patients with high-risk neuroblastoma. This region, which corresponds to coordinates 0-40 on the R27 map has been called the Tra2 region, and is believed to be involved in mating pair formation. Meanwhile, the random lasing wavelength of the short-range disorder POF because of a small scattering mean-free path has been found to be blue shifted with respect to the long-range disorder POF, which will give a way to control the random lasing wavelength.

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It is concluded that thiazolidinediones may have a role in the management of non-diabetic proteinuria of various aetiologies. The axonal damage marker tau protein in the cerebrospinal fluid is increased in patients with acute encephalopathy with biphasic seizures and late reduced diffusion. The gross national income per capita for the country is a strong predictor for use of these treatments, suggesting that economics influence under-treatment. Cardiomyocytes (H9c2) derived from embryonic rat heart cell culture were exposed to either normothermic (37 degrees C) or hypothermic (31 degrees C) environments before undergoing oxidative stress via treatment with hydrogen peroxide (H(2)O(2)).

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Association between the cytotoxicity of thymidine and tumorigenicity of clones derived from C3H/10T1/2 mouse embryo fibroblasts. Significance of vesico-uretero-renal reflux in the course and prognosis of urinary tract infections in childhood Chondrosarcoma were composed of 20 conventional chondrosarcoma (10 grade 1, seven grade 2, and three grade 3), two dedifferentiated chondrosarcoma, two clear cell chondrosarcoma, and two myxoid chondrosarcoma. Influx of Na and Isc were increased by vasotocin in the adult but not larval skin.

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The decline in clubroot formation was accompanied by a reduced number of fungal structures within the root cortex and slower development of the fungus. Minimally Invasive Robotic Laser Corpus Callosotomy: A Proof of Concept. Effect of shenluotong decoction on renal interstitial fibrosis in rats with obstructive nephropathy Potentiation was observed with a proline concentration normally present in human CSF (3 microM). Pulmonary endothelial NOS levels increased and alveolar vascular staining was enhanced after bile duct ligation.

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We analyzed plasma of healthy volunteers (asymptomatic negative controls), participants with gastrointestinal (GI) illness but without recent fish consumption (symptomatic negative controls), and participants with GI illness who had recently consumedfish. All drugs produced deep anesthesia with burst suppression and no response at the highest concentrations.

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CD137 (ILA/4-1BB), a member of the tumor necrosis factor (TNF) receptor family, promotes adherence and prolongs survival of human peripheral monocytes. Paraffin-embedded tissue sections from six patients with GCA and five patients with PMR were available for immunohistological analysis of chemokine receptor expression. In 1,336 patients receiving general anesthesia, seven airway measurements were made to reflect degree of difficulty and predictive value of presurgical tests on direct laryngoscopy and intubation. Physiologic mechanism and preoperative prediction of new-onset dysphagia after laparoscopic Nissen fundoplication.

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Iridium phosphinidene complexes: a comparison with iridium imido complexes in their reaction with isocyanides. Use of these inhalers is difficult and often poorly taught to patients. Search for a more adequate test to predict the long-term migration from the PVC gaskets of metal lids into oily foods in glass jars. Magnetisation transfer ratio (MTR) and T1 relaxation time are abnormal in normal appearing tissues in established MS.

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These findings support the hypothesis that smaller yet abnormal parathyroid glands can be suppressed and may become hypersecretory if left in situ after surgical removal of the larger gland. Rapid and objective preoperative assessment of patients undergoing carotid endarterectomy (CEA) remains problematic.

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She was diagnosed with pneumonia and discharged home with antibiotics. Molecular mechanisms of leukocyte trafficking in T-cell-mediated skin inflammation: insights from intravital imaging. Radiofrequency ablation of resistant atrial flutter: a new anatomical approach

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The strain images of the homogeneous and layered phantoms showed some artifacts that need to be corrected for, to obtain images of the modulus of elasticity. The cell viability indices showed a similar dual phase to the HIF-1alpha expression, while the apoptotic indices started to increase as the level of the HIF-1alpha expression decreased. Anabolic androgenic steroids differentially affect social behaviors in adolescent and adult male Syrian hamsters. We also found subtle reductions in gray matter in the right hippocampal formation in carriers of the risk variant.

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Progressive epitope-blocked panning of a phage library for isolation of human RSV antibodies. There was also an inverse correlation between triglyceride concentration and HDL2. Evidence supports bone-specific drugs (BSDs) efficacy in the fracture risk reduction. Previous studies have demonstrated recovery with laser nerve welding (LNW), a novel alternative to microsuture.

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Mutation of Trp(39), Tyr(69) and Tyr(88), which are required for agonist binding, in the GLP-1R abolished cell surface expression of the receptor independent of the SP cleavage or N-linked glycosylation. LF samples were collected from 166 patients with LCSS, and from 167 controls who underwent lumbar magnetic resonance imaging (MRI) as part of a routine medical examination. Evaluation of pulmonary GGO and investigation of the correlation between CT imaging features and lung adenocarcinoma subtypes or driver genes can be helpful in confirming the diagnosis and in guiding the clinical management. Implications of foliar terpene content and hydration on leaf flammability of Quercus ilex and Pinus halepensis.

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Large-area broadband saturable Bragg reflectors by use of oxidized AlAs. We report a cerebrovascular accident after Ecstasy (MDMA) intake which induced a frontal dementia in a young man. Parenteral Nutrition (PN) is used when gut fails to provide complete nutrition.