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Arcolane (Ketoconazole)

Arcolane is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus. Arcolane was first approved in an oral formulation for systemic use by the FDA in 1981. At this time it was considered a significant improvement over previous antifungals, miconazole and clotrimazole, due to its broad spectrum and good absorption. However, it was discovered that Arcolane produces frequent gastrointestinal side effects and dose-related hepatitis. These effects combined with waning efficacy led to its eventual replacement by triazole agents, fluconazole, itraconazole, [voraconazole], and posaconazole. Arcolane and its predecessor clotrimazole continue to be used in topical formulations.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Arcolane cream and prescription shampoo are also sometimes used to treat dandruff and seborrheic dermatitis (condition that causes flaking of the skin). Arcolane cream is sometimes used to treat tinea manuum (fungal infection of the skin on the hands). Arcolane cream is also sometimes used with other medications to treat skin conditions that are often worsened by fungal infection such as diaper rash, eczema (skin irritation caused by allergies), impetigo (blisters caused by a bacterial infection), and psoriasis (a lifelong skin condition). Talk to your doctor about the possible risks of using this drug for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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Expression of the fibroblast growth factor-like protein EGL-17 and its receptor EGL-15 is reduced in vrk-1 mutants, suggesting that VRK-1 might act at least partially through activation of FGF signaling. Identification of RIP-II toxins by affinity enrichment, enzymatic digestion and LC-MS. Echocardiography plays an important role in defining dyssynchrony which is key to optimal patient selection. Intradural nonneoplastic cysts compressing the spinal cord are rare lesions. Easy oxydation of phosphatidylcholin (lecithin)--the main membrane component--is the limitation of the introduction of liposomes to the medicinal practice in a broader scale.

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As the extent of linkage disequilibrium across cattle breeds is limited, the underlying causative mutations have been mapped to a small genomic interval containing two promising candidate genes. Retrospective evaluations of the relevance of primary colorectal cancer (CRC) location consistently indicate that right-sided tumors, arising in the cecum, ascending colon, hepatic bend, transverse colon and splenic flexure, are clinically, biologically and genetically different from left-sided tumors - those located in the descending colon, sigmoid colon or rectum. To determine whether preoperative, postoperative, or change in keratometry can be used to predict visual outcomes in hyperopic LASIK.

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We propose a lattice solution model which adds interactions with water molecules to lipid-lipid interactions and obtain its thermal properties under a mean-field approach. It is therefore essential to understand quantitatively how CCFs are shaped by different factors, such as connectivity, synaptic parameters, and background activity. The present study constitutes an effort to explore the graduated metabolic impact of the different PCOS phenotypic groups through the levels of adiponectin, an adipose-derived hormone, in 100 normal weight, normoinsulinemic patients with PCOS. While tumor cells did not produce significant amounts of MMP-2 or MMP-9, the presence of tumor was associated with increased levels of MMP-2 expression by mouse ovarian stroma.

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The time from earthquake onset to the peak in patient admissions and surgeries differed between the 2 earthquakes. Comparison of these results with those reported on other dityrosine-dimerized proteins suggests that while the conformation of these proteins might not be altered in a major manner upon dityrosine linkage, the dimer is structurally less stable and displays reduced solubility, both of which are of pathological importance. Stereoisomer compounds possess the same molecular and structural formula, but they differ in their three-dimensional configurations. In a recent laboratory experiment on the interaction between a plant, bishop pine (Pinus muricata), and a root-symbiotic ectomycorrhizal fungus, Rhizopogon occidentalis, we demonstrated the potential for selection mosaics in that interaction, and the existence of substantial within-population genetic variation for symbiotic compatibility in the interaction.

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Auditory-motor entrainment and phonological skills: precise auditory timing hypothesis (PATH). Age, gender, ratings of depression and other confounding variables were used to control for changes in patient population over time.

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Differential display (DD) was conducted to compare the blood of tumor-free individuals with the blood of patients with lung, breast, and colon cancers. The effect of PEG coating on in vitro cytotoxicity and in vivo disposition of topotecan loaded liposomes in rats. These data suggest that binding of DNA in solution induces conformational changes in CRP which can be transmitted via intersubunit contacts to regions of the protein involved in interactions with other members of transcriptional machinery. A micropolar fluid is the fluid with internal structures in which coupling between the spin of each particle and the macroscopic velocity field is taken into account.

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A novel nasal drug delivery system based on interactive mixtures has previously been developed, where fine particles of the active component are adhered to the surface of mucoadhesive carrier particles by dry mixing. Coding of images of materials by macaque inferior temporal cortical neurons. The realized instruments were flown from stratospheric balloons within the framework of European campaigns for the study of stratospheric ozone and water vapor and were involved in the validation of the ODIN and ENVISAT satellites. Hepatitis associated with herpes viral infection in the tortoise (Testudo horsfieldii). A total of 46 patients and 46 healthy controls underwent neurocognitive testing.

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Evidence-based criteria and more-sensitive risk-adjustment techniques must be employed if data on quality are to yield fair comparisons among health plans. This study aimed to determine whether magnesium as a lightweight and biocompatible metal is suitable as a biomaterial for spinal implants based on its MRI artifacting behavior. Complications from the use of skin lightening agents were seen in a few students. To define the accuracy of multiparametric magnetic resonance imaging (MP-MRI) for identifying focal and established extracapsular extension (ECE) in various zones of the prostate. Studies exploring innovative techniques based on CSF have reported interesting findings for the combination of amyloid beta (abeta) isoforms as well as alpha-synuclein, and there are interesting results emerging from preliminary studies applying proteomic techniques.

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The influence of fluvastatin on plasma lipids and on platelet aggregation and fluidity was studied. Clinical efficacy of sildenafil in primary pulmonary hypertension. Importantly, 12 monthly infusions of tocilizumab improved nailfold capillary changes as well as skin sclerosis in a patient with diffuse cutaneous SSc. This kit has been developed in accordance with the standards of the forensic community as defined by the DNA Advisory Board. In this paper, we derive and analyse a novel mechanistic stage-structured simulation model for Culicoides biting midges-the principle vectors of bluetongue and Schmallenberg viruses which cause mortality and morbidity in livestock and impact trade.

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Due to the lack of classical HLA antigens on the trophoblast, fetal antigens are possibly presented in a non major histocompatibility complex (MHC) restricted way. The roles of the medial prefrontal cortex and striatum in reputation processing. Hypothalamic nitric oxide synthases (NOS) activities were significantly increased in IL rats, as the catalytically active neuronal NOS (nNOS) dimers compared to controls. Our results suggest that the biofilm populations were taxonomically distinct from the planktonic community and were enriched in populations with a chemolithoautotrophic and diazotrophic metabolism coupling hydrogen oxidation to energy conservation under oligotrophic conditions.

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This study analyzed the direct short-term effect of vagus nerve stimulation (VNS) on respiratory sinus arrhythmia (RSA) in children with pharmacoresistant epilepsy. Reactivating and protective effects of Pro-2PAM in mice poisoned with paraoxon.

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Clinical features of genetic hemochromatosis in women compared with men. Ageing of Mexican population implies greater demand of hospital services. In a secondary analysis of data collected for a published study of depression and prognosis in patients with CHF, we examined the relations among anxiety, depression, and prognosis. Pilot studies have shown that phenotyping of circulating tumor cells could be used to predict response to targeted therapies.

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A human Raf-responsive zinc-finger protein that binds to divergent sequences. The morphology of the vascular spasm in cerebral aneurysm rupture signaling molecules and epithelial-mesenchymal transition (EMT) markers was assessed by Western blotting. The content and structure of the Delphi study was informed by the results of the literature review.

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Complete remission of palmoplantar psoriasis through Helicobacter pylori eradication: a case report. CLINICAL PRESENTATION: A 15-year-old girl presented with a hypothalamic hamartoma associated with intractable gelastic and tonic seizures. In vivo and in vitro biosynthesis of free fatty alcohols in Escherichia coli K-12. Nine of 11 clones recovered from methycellulose were initiated by diploid cells.

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A retrospective, descriptive study of cases observed in the department of dermatology of Sfax hospital over a period of 11 years (1995-2005). We demonstrated the capability of a highly elevated proportion of stx2-positive, but constitutively Stx2-negative, E. The protein is retained in the cytoplasm during early embryonic cleavage stages but returns to nuclei at the mid-blastula transition.

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A case of Ullrich-Noonan syndrome with pulmonary stenosis, epicanthus, ptosis, small stature, curved tibia, positive sex chromatin, and a diploid chromosome number is presented. Endovascular treatment of abdominal aortic aneurysms in octogenarians Dietary intake of specific nutrients or food groups during pregnancy could play a role in the risk of asthma and atopy in offspring, but specific dietary patterns have not been implicated. Furthermore, the existing literature on the construct of psychopathy in youth is not sufficient to justify its use for most forensic purposes. In thirteen of the patients fractures of the femoral head were noted, four being transchondral and nine of the indentation type.

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The Mig10/RIAM/Lpd (MRL) adapter protein Lpd regulates actin dynamics through interactions with Scar/WAVE and Ena/VASP proteins to promote the formation of cellular protrusions and to stimulate invasive migration. We applied subtractive genomics approach for the identification of novel antimicrobial targets in Xanthomonas oryzae pv. Following ECP administration, both 70F and 100F desmosomes are present between EMG cells.

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In addition, the classification system should be robust enough to last over time and provide comparability between data collections. Effect of Positive Psychological Intervention on Well-Being, 2-Week Illness Prevalence, and Salivary Immunoglobulin A. Comparison of smoking cessation between education groups: findings from 2 US National Surveys over 2 decades. We conjecture a role for CCR2 as a coreceptor for HIV-1 infection and map the HIV-1 binding site to the amino-terminal part of this receptor. Early-life adversity is a well-established risk factor for the development of depression later in life.

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These signs suggested multifocal disease associated with the cerebrum and cerebellum. Determination of the optimal model for end-stage liver disease score in patients with small hepatocellular carcinoma undergoing loco-regional therapy.

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Among the isolated compounds, 5,6-dibromo- N,N-dimethyltryptamine ( 1) exhibited significant antidepressant-like action in the rodent FST model, while 5-bromo- N,N-dimethyltryptamine ( 2) caused significant reduction of locomotor activity indicative of a potential sedative action. Sex differences and hormonal modulation of ethanol-enhanced risk taking in rats. Therapeutic impact of streptococcal and enterococcal bacteremia in hematology patients We examined availability of certain drugs in Guatemala and found that CAFTA intellectual property rules reduced access to some generic drugs already on the market and delayed new entry of other generics.

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It requires the assessment of risk factors for the patient as well as of a potential source of bacteremia. Using two differential equation models (Water-Phytoplankton and Water-Phytoplankton-Dissolved Organic Carbon) we here examine previously reported non-linearity between purpose aricept medication results BCF and K(ow). Olsalazine was not better than placebo in maintaining remission in inactive Crohn disease.

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TCF21 rs12190287 Polymorphisms Are Associated with Ventricular Septal Defects in a Chinese Population. Hence, epidemiological studies make up the bulk of evidence for nutrition guidelines. Reasons for transfusing group O blood to ABO non-identical recipients were also assessed. By means of density functional theory (DFT) calculations on isolated molecules and dimers, we have found that both the frequencies and intensities of the strongest Raman lines (R mode) are strongly influenced by intermolecular interactions. The data suggest that interaction with nucleolin is, at least in part, responsible for nucleolar accumulation of La and that npLa atorvastatin cost uk approximately may be involved in ribosome biogenesis.

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Although animal models have been invaluable in delineating the mechanisms of immune two major drug interactions of simvastatin 20 function, their precision in predicting how well specific vaccines work in humans is often suboptimal. Lymphocyte interferon production and transformation after Herpes simplex infections in humans. Regulation of phosphodiesterase 3 in the pulmonary arteries during the perinatal period in sheep. The cytoplasm is abundant and eosinophilic, and many of the neoplastic cells contain prominent vacuoles. To compare the efficacy of fluticasone propionate (FP) and zafirlukast (Z) in younger (12 to 49 years of age) versus older (50 years and older) patients with asthma.

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tranSMART, however, currently lacks interactive and dynamic visual analytics and does not permit any post-processing interaction or exploration. To develop a simple and rapid protocol for detecting deletions of the Y chromosome and to evaluate the feasibility of gene-based screening in men with spermatogenic failure. Our study represents an example of the utilization of qualitative research methods to investigate the appropriateness of the Rheumatoid Arthritis Quality of Life Scale (RAQol) for the assessment of Qol in Estonian patients. In 9 experiments, participants searched for a nonsalient target (vertical among tilted bars). One-year outcomes were mostly similar across groups, however, increases in the proportion of offenders employed, receiving income from employment dark souls carim names that start with j and family or friends, and being paid for work were significantly greater among the received-employment-services group, and a greater proportion of this group also completed drug treatment.

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