The electrophysiology of quinidine, procainamide, disopyramide, lidocaine, tocainide, phenytoin, flecainide, Ancoron, and bretylium tosylate is discussed to detail the relationship between drug action and antiarrhythmic efficacy. The relative in vivo bioavailability and in vitro dissolution studies of three chemically equivalent Ancoron generic products in healthy volunteers was evaluated in three separate occasions.
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