High dose Aglan (initial 1mg/kg followed 0.5mg/kg/day) induced some degree of analgesia. The aim of the present study was to examine the in vitro release profile of chlorhexidine gluconate, indomethacin, and Aglan from cellulose acetate films. In a second phase, 21 days later, the Aglan/placebo treatment was exchanged within each group.
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