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Neosar (Cyclophosphamide)
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Cyclophosphamide

Neosar is a potent immunosuppressant that can decrease the immune response by blocking the production of DNA in cells. Neosar is used for severe complications of lupus, systemic sclerosis (scleroderma), some forms of vasculitis, myopathies, such as polymyositis and dermatomyositis; and sometimes rheumatoid arthritis.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Enap, Tegrital, Indophtal, Restyl, Desyrel, Lazon, Minisec, Rimox, Rofenac, Lasoprol, Ramipril, Eupantol, Dapoxetine, Unigyl, Eeze, Wellbutrin, Vitaros, Cusiviral, Calton, Clavamox, Takepron, Actalipid, Mittoval, Anamet, Venlax,

Neosar is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth. Neosar also works by decreasing your immune system's response to various diseases. It is used to treat a certain type of kidney disease in children after other treatments have not worked. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used for various conditions such as lupus and rheumatoid arthritis, and to prevent organ transplant rejection.

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All relevant English-language studies identified in searches of the MEDLINE (1966 to December 2000), HealthSTAR (1975 to December 2000), and Cochrane Library databases, and references lists of key articles. Under the consideration of known elimination kinetics and the individual smoking status (biomonitored with nicotine metabolite cotinine and tobacco specific hemoglobin adduct: N-(2 cyan ethyl) valines, CEV), the data allow theoretical extrapolation to the initial protein adduct concentrations at the time of the accident (the MEV/CEV levels were from 1,616 pmol/g globin to 1,880 pmol/g globin and HEV/CEV levels from 1,407 pmol/g globin to 5,049 pmol/g globin, and correlated with inhaled 0.4-1.5 ppm ethylene oxide.

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Tissue responsiveness to a hormone is dependent on the amounts of its receptor expressed under physiological conditions. There were 10 males and 6 females at the age of 20-63 years (mean, 41 years). For a better understanding of the underlying mechanisms, there is a need for comprehensive epidemiologic studies.

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It also shows that the tissue damage that remains after enhancement ceases is more severe in secondary progressive disease. To evaluate the efficacy of the combined drug furamag (furasidine potassium and magnesium hydroxycarbonate) in combination with the third-generation cephalosporin cefotaxime versus cephalosporin monotherapy for nosocomial urinary tract infections (NUTI). Sensitization of tumor-associated endothelial cell apoptosis by the novel vascular-targeting agent ZD6126 in combination with cisplatin. Action of angiotensin on uptake, release and metabolism of 14C-noradrenaline by isolated rabbit hearts. Major changes occur in the cardiovascular, pulmonary, endocrine, and immunological systems, and, if untreated may soon result in cardiovascular collapse and somatic death.

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The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the golden hamster model. TaSERK transcripts could also be enhanced by epibrassinolide and abscisic acid. Negativity bias, which describes the tendency to interpret ambiguous stimuli or events as negative, is often observed in patients with depression and may prevent psychological well-being.

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Treatment with adrenocorticotropic hormone and trigeminal neurotomy also resulted in recrudescence of IBRV, but immunosuppression was not detected in these animals. Morphological criteria for differentiation of mycoplasmas and oncornaviruses This article overviews the rational design of this new class of molecules, their specific molecular features (receptor specificity, biological properties, etc.) and whenever available, the data that have been obtained in cell or animal models of breast cancer.

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Modulation of the immune response to peritoneal injury may prevent postoperative adhesion formation. We report a case in which chemotherapy with paclitaxel (TXL) infused systemically and intraperitoneally was effective for gastric cancer with malignant ascites. rcl may play an important role during cellular proliferation and c-myc-mediated transformation. A dipeptide taste ligand L-aspartyl-D-2-aminobutyric acid-(S)-alpha-ethylbenzylamide was found to be about 2000 times more potent than sucrose. A rare of chronic polypous rhinosinusitis with concomitant manifestations of acute trichinosis

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At the inter-specific level, high-elevation species showed higher survival values than low elevation ones, likely because a greater allocation to self-maintenance permits species to persist in alpine environments. Mechanism of in situ surface polymerization of gallic acid in an environmental-inspired preparation of carboxylated core-shell magnetite nanoparticles. We suggest that in SUNCT patients high-resolution magnetic resonance imaging (MRI) and/or DTI-MR tractography should be performed to exclude neurovascular compression.

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We then analyzed the literature with respect to the historical evolution of this concept, current guidelines regarding the acceptance of donors with stones and stone related morbidity in recipients and donors. Expression of DNA encoding residues 1141 to 1279 of FHA in Escherichia coli yields a protein of 18,000 Da that exhibits some of the carbohydrate recognition properties of FHA (S.

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C(H)-region effects on affinity and specificity suggest new mechanisms for generating antibody diversity and polyreactivity (multispecificity) that impact current views on idiotype regulation, autoimmunity, and B cell selection and change our understanding of vaccine responses. Adult, male Sprague-Dawley rats were given either lipopolysaccharide or sterile saline via a jugular vein cannula. Twenty-six patients with fracture-dislocations of the elbow were reviewed retrospectively. This persistence of PGL-I in the lesions paralleled high serum anti-PGL-I antibody titers but was not indicative for the presence of viable bacilli in the lesions. This study assesses intravascular density produced by ionic and nonionic contrast material and its effect on visualization of stenoses by CT angiography.

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The aim of this study was to evaluate the performance of two relatively new quantitative D-Dimer assays (Innovance and AxSYM) by comparison with a clinical gold standard. Identifying patients with hereditary risk requires documentation of appropriate family history, and recent studies have characterized criteria for identifying women most likely to have inherited mutations in these genes. We compared outcomes in pregnancies fathered by renal transplant men per whether they had been exposed to MPA or not at time of conception.

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The degree of expression of the integrin alpha5 subunit correlated well with the strength of glioma cell adhesion to fibronectin rather than that of migration to the molecule. These antibodies also recognised distinct proteins in the peritrophic membrane which is secreted into the midgut to enclose a bloodmeal. Spontaneously active type II/III units had intermediate properties.

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Associated malformations in infants with cleft lip and palate: a prospective, population-based study. In registration studies, deferasirox tablets were dispersed in non-carbonated water prior to administration. Disease Risk Assessment Using a Voronoi-Based Network Analysis of Genes and Variants Scores.

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Traumatic oesophageal perforation may occur during the intensive care of premature infants due to trauma of the laryngoscope blade, to traumatic intubation with an endotracheal tube or to forced passing of a nasogastric tube. These are not suitable for the description of reproducible transient sequential neural dynamics.

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We performed echocardiographic measurements before and immediately after loading of amrinone, and evaluated its cardiovascular effect. The prevalence of chronic renal failure is increasing because of increase in chronic debilitating diseases and progressing age of population. Translational regulation of XIAP expression and cell survival during hypoxia in human cholangiocarcinoma.

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Infectious complications with plasmapheresis in rapidly progressive glomerulonephritis. We will also evaluate the effect of the intervention on secondary outcomes which include the effect of the intervention on hospital utilization for pain crisis, quality of life, adherence to analgesic medications, barriers to pain control, anxiety and patient engagement. However, the practitioner should pay attention to the composition and the polish of soldering silver-based alloys containing copper and zinc in order to limit cytotoxic ion release. Insulin receptors in mouse brain: age-related modifications are corrected by thymus graft. The data do not support the concept of increased protein leakage in the exchange vessels after bypass.

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Submandibular salivary gland tumors: Clinical course and outcome of a 20-year multicenter study. Percutaneous ultrasonic lithotripsy (PUL) after shock wave lithotripsy (SWL) failure. The pregnancy outcomes of patients delivering infants after LRYGB at our institution were compared with those of control subjects (stratified by body mass index) who had not undergone WLS.

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pylori-infected subjects and if these are predictive of progression to H. To help general practitioners (GPs) conduct more comprehensive medication reviews for patients with multimorbidity, we developed the theoretically-informed MultimorbiditY COllaborative Medication Review And DEcision Making (MY COMRADE) implementation intervention. The value of three-dimensional helical computed tomographic angiography in the diagnosis of pelvi-ureteric junction obstruction caused by crossing vessels. Natural knockout mice of aggrecan, termed cartilage matrix deficiency, and LP-null mice exhibit decreased levels of aggrecan depositon in cartilage and correspond well with their phenotypes such as dwarfism and spinal misalignment, demonstrating in vivo roles of the aggregate in cartilage development and homeostasis. Ag NP sizes were controlled by changing molecular weights of PDHSt of the block copolymer.

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The RNA pools can be recovered from the NMR tube after measurement of NMR spectra. The proximal right corpus was distended and separated from the distral flaccid corpus by a transverse membrane. To this aim, we focussed on Drosophila midgut, a hierarchically organized and well characterized model for stemness analysis. A tissue sectioner which uses a vibrating razor blade and a simple mechanism for the elevation of the tissue can be constructed for less than fifty dollars. We aimed to assess a serological biopsy using five stomach-specific circulating biomarkers-pepsinogen I (PGI), PGII, PGI/II ratio, anti-Helicobacter pylori (H.

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A data set consisting of 24 inhibitors was selected on the basis of the information content of the structures and activity data as required by the Catalyst/HypoGen program. As adipogenesis progresses, there is a significant increase in the expression level of PKA regulatory subunits and a corresponding decrease in PKA activity.

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Epidemiological studies have suggested a protective effect of dietary fiber intake on breast cancer risk while the results have been inconsistent. With this method also different stages of mitosis can be visualized by analysing various steps of spindle formation. The symptoms of this disease with dyspepsia can be anorexia, abdominal distention, bellyache, and loose stools. However, the effect infant-directed action on infant behavior is understudied. Evidently, characteristics of the scintillator used in radioimmunoassays where beta-particle emitters are counted should be carefully examined if results are to be optimal.

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Using a multimethod approach to develop implementation strategies for a cervical self-sampling program in Kenya. Gas6-mediated Axl signaling, which is enhanced and diversified in the presence of Sunitinib possibly contributes to acquired chemoresistance, recurrence of aggressive disease and metastasis of CCRCC tumors. An update on 73 US obese pediatric patients treated with laparoscopic adjustable gastric banding: comorbidity resolution and compliance data. IL11 administered for 5 consecutive days beginning 2 h after total-body irradiation with 8 or 9 Gy 60Co gamma rays resulted in a significant increase in 30-day survival.

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Motility is not a good enough criterion on which to prove the presence of viral elements, either in the medium or on the sperm. HPCP offers one educational group visit each trimester to improve knowledge of self-care during pregnancy and of childbirth and infant care.

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This may be due to the presence of global hypoxia in the HI model which can upregulate vascular endothelial growth factor and subsequent proliferation of endothelial cells. To examine the trends of healthcare use and costs for patients with type 2 diabetes mellitus (T2DM) in Taiwan over the last decade, and to identify factors associated with high healthcare cost and poor diabetes care. In order to understand the mechanisms underlying these changes, we characterized the fate of various cytoskeletal filaments and investigated the nuclear/cytoplasmic compartmentalization of infected cells. Viral infections can trigger tissue destruction through innate and/or adaptive immune mechanisms.

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Spinal cord stimulation is an increasingly popular form of pain treatment. These glycines may be necessary for the larger conformational change needed for an induced fit mechanism upon binding RNA. Advances in the study of the relationship between autophagy and sepsis-induced lung injury

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We previously demonstrated that ghrelin elicits GH secretion directly in somatotrophs by activating two major signalling cascades, which involve inositol phosphate and cAMP. In this study the authors sought to determine whether any correlations existed between postimplantation head CT findings and the need to perform decompression surgery in patients with grid electrodes. Method for the multichannel polarography of the oxygen in biological objects The reconstruction of healthcare systems in developing countries after natural disasters is poorly understood. Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.

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Treatment of pain should proceed in a step-wise fashion providing medications appropriate for treating the level of pain. However, a linear relationship has been demonstrated for the first time between coupling constants and X-H distances for different X atoms by plotting the ratios of the coupling constants for complexes and corresponding monomers versus the ratios of distances for complexes and corresponding monomers times the square of the Pauling electronegativity.

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Nuclear magnetic resonance analyses of lipopolysaccharides from mutant and complemented strains suggest that lag-1 is responsible for O acetylation of serogroup 1 O polysaccharide. This somatic event is consistent with a proliferative monoclonal lesion. Hearts exposed to reversible ischemia stand a subsequent prolonged episode of coronary artery occlusion (ischemic preconditioning) better. The rs112735431 polymorphism of the RNF213 was evaluated by polymerase chain reaction amplification of target and detection by restriction fragment length polymorphism analysis. Foreign bodies in the larynx and tracheobronchial tree in children.

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Operational regimes for a simplified one-step artificial chaperone refolding method. Prevalence, predictors, and consequences of late nephrology referral at a tertiary care center. Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor.

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An inactive open complex mediated by an UP element at Escherichia coli promoters. Mechanisms that inactivate the p53 pathway in Acute Myeloid Leukemia (AML), other than rare mutations, are still not well understood. We carried out a laboratory investigation of temperature effect on survival as well as reproductive and trophic activities of mesostigmatid mites. Docking experiments support the conclusion that bulgecin A co-ordinates to the zinc II site in metallo-beta-lactamases via the terminal sulphonate group on the sugar moiety.

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Five hundred nineteen consecutive patients with SLE were studied, with follow-up ranging from 4 to 7.8 years. The novel use of an external fixator connecting rod and synthetic bone substitute to achieve anatomic reduction of depressed tibial plateau fracture fragments. However, VL is associated with hypervolemia, which may cause tissue edema, cardiopulmonary complications and a prolonged hospital stay.

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A 18-year-old female had low grade fever, butterfly rush, proteinuria, leukocytopenia and hypocomplimentemia in 1988, and she was diagnosed as systemic lupus erythematosus (SLE) with lupus nephritis (WHOIIb). A neuro-ethological view of hoarding as a spectrum symptom seen not only in OCD, but also in other disorders, may provide a useful heuristic for current clinical practice and for future empirical research.

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Alicyclic amine sulphotransferase in human liver cytosol was purified to homogeneity by anion exchange, affinity and hydroxyapatite chromatography. Data for establishing the MPEL of trimethylethylene oxide in the air of a work area Conservative management of a patient with lumbar disc disease: averting lumbar disc surgery. Medians, percentiles, and confidence intervals were calculated, and the Mann-Whitney U and Kruskal-Wallis H tests were used, where appropriate. The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin.

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This prospective study, although not randomized, suggests that, except for invasiveness to the muscular layers of the abdominal wall, there may be no substantial difference between AWL and insufflation or among subcutaneous lift, peritoneal lift or insufflation in terms of morbidity, mortality, preparation time, operating time, inflammatory reactions, and postoperative clinical course. We comment on the following questions: Do specific RS factors influence health outcomes?

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Structural changes in the actin-myosin cross-bridges associated with force generation induced by temperature jump in permeabilized frog muscle fibers. The prevalence of hiatal hernia is low and esophageal motility disorders are moderate. Our findings suggest that this clinical behavior is from elastolysis as a result of inflammation. These results suggest that hippocampal CaMKII is critically involved in the development of morphine tolerance and dependence, and inhibition of this kinase may have some therapeutic benefit in the treatment of opiate tolerance and dependence. When categorized according to DEXA, there were no relationships between body fat and cognitive function in the whole group, but women in the middle and highest tertiles of DEXA body fat had better executive function than those in the lowest tertile.

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Expression of ICAM-1 was significantly decreased at 7 weeks, find 20 mg sildenafil as compared to fresh and 2-week groups, with no statistically significant difference between fresh and 2-week nerves. Clinical or electroclinical seizures recorded by continuous EEG monitoring were numerous, leading to status epilepticus in three babies. Besides the treatment indicator we also have information about a time-varying covariate that may be of importance for the survival endpoint.

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This cell line had much stronger mRNA expression of Dicer, an RNase III-like enzyme, than did human osteoblastic MG63 cells. A chemical substance used as a photoinitiator for light-cure resin compositions, D,L-camphorquinone (CQN) was found to be weakly antiandrogenic in vitro. Expert investigators were identified based on their ability to 1) consistently obtain high quality dapoxetine manufacturers in pakistan aeroplane data from cases 2) achieve a high rate of completion of case investigation questionnaires, 3) identify the most likely source of the disease-causing agent, and 4) identify any possible links between cases.

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PDGF and PDGF receptors are widely expressed in neuronal and glial cells of many regions of both the central and peripheral nervous systems. Percutaneous aortic valve replacement with the CoreValve prosthesis. We also illustrate the proposed methods by analyzing primary magazine online taromentin biliary cirrhosis (PBC) data.

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In this review we provide a comprehensive analysis of the literature in context of the role of annexin II in angiogenesis, tumor progression and metastasis. The deep divergence time estimated between these two species sets a lower bound on the time that Demodex have been coevolving with their mammalian hosts, and supports the hypothesis that there was an early split within the genus rob holland pantoprazole dosage Demodex into species that dwell in different skin microhabitats. Ovarian histopathology was classified as normal, functional ovarian cyst, benign ovarian tumor, endometriosis, ovarian cancer, and metastatic cancer. Finally, using transcriptional fusions of dprA to the Escherichia coli lacZ gene, we show that expression of dprA::lacZ requires tfoX and that the presence of multiple copies of tfoX abolishes the temporal regulation of dprA, resulting in its constitutive expression.

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The main dental character uniting all palaeospinacids is the very specialised pseudopolyaulacorhize root vascularisation. The left side, right side, and swallowing threshold masticatory tests were made with peanuts and carrots before treatment and 16 weeks after the prosthesis insertion (baseline) and thereafter at 6, 18, 36, and 60 months. To examine factors associated with treatment default among tuberculosis (TB) patients registered for treatment in 2000-2001. The body representation in the second somatic sensory area of macaques clotrimazole miconazole econazole and ketoconazole shampoo has been studied by tracing with anatomical techniques the projections from defined parts of the body representation in the first somatic sensory area (SI) to their terminal regions within the lateral sulcus. Foreign bodies located at the base of the skull pose a surgical challenge.

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Regarding the patient perspective, it is advised to involve organisations for older people or informal carers in the inventory of problem areas, and additionally to perform literature research metformin hydrochloride sustained release tablets 500mg magnesium of patient values on the subject. The development of endometrial cancer, as well as drug resistance in breast cancer patients undergoing tamoxifen therapy, may represent altered ER-alpha function secondary to specific exon deletions. We report an acute right-sided functional hemiballistic syndrome of the upper and lower limb combined with functional choreatic symptoms of the right forearm and hand of an 59 year old drummer.

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CAB consists of six short tests measuring speed and attention, memory, visuospatial functions, takepron od tablets language, and executive functions. These require behavioral management to avoid long-term deleterious sleep habits. Here, we proposed a novel strategy that transforms circular transcripts to pseudo-linear transcripts and estimates the expression values of both circular and linear transcripts using an existing model-based algorithm, Sailfish.

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The correlation of miR-421 to GC clinicopathological features as well as the diagnostic value of miR-421 comparing to carcinoembryonic antigen (CEA) and cancer antigen 125 (CA-125) were analyzed. An impaired hypothalamopituitary axis and stress reactivity have extensively been discussed without convincing experimental evidence. The TAOS is a prospective, multicenter randomized trial comparing 18-month outcomes after transtibial amputation using the Ertl versus Burgess approach among adults aged 18 to 60. Regarding socioeconomic status, only in the younger age group was lower status associated with lower augmentin 1 mg prezzo kenya prevalence of prescribed therapy.

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The higher level of protection achieved by the administration of the inducers and the vaccine was shown to be due both to interferon production and activation of cellular immunity mechanisms. The primers successfully amplified nxrA gene sequences from Nitrococcus mobilis, but not fenac nh 2012 best from Nitrospira marina. Carnitine plasma levels and fatigue in children/adolescents receiving cisplatin, ifosfamide, or doxorubicin.